Primary Combined Hepatocellular-Cholangiocarcinoma: A Case of Underdiagnosed Primary Liver Cancer

被引：3
作者：
Ayas, Mohamad F. [1 ]
Affas, Saif [1 ]
Ayas, Zayd [2 ]
Chand, Momal [3 ]
Hadid, Tarik [4 ]
机构：
[1] Ascension St John Hosp, Internal Med, Detroit, MI 48236 USA
[2] Univ Texas Austin, Coll Nat Sci, Basic Sci, Austin, TX 78712 USA
[3] Ascension St John Hosp, Pathol, Detroit, MI USA
[4] Ascension St John Hosp, Oncol, Detroit, MI USA
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2021年 / 13卷 / 09期
关键词：
hepatocellular carcinoma (hcc); cholangiocarcinoma; combined hepatocellular-cholangiocarcinoma; trans-arterial radioembolization; liver tumor; CARCINOMA; TRANSPLANTATION; FEATURES; OUTCOMES;
D O I：
10.7759/cureus.18224
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Combined hepatocellular-cholangiocarcinoma (CHC) is a rare primary tumor of the liver. Histologically, it comprises components of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) but is associated with a worse prognosis. International guidelines regarding its management are scarce, with surgical management (major hepatectomy) being the treatment of choice. In this report, we present a challenging case of a 73-year-old male with primary CHC who was not a surgical candidate but underwent hepatic artery radioembolization instead.
引用
收藏
页数：6
相关论文
共 50 条
  • [41] Clinicopathological Characteristics in Combined Hepatocellular-Cholangiocarcinoma: A Single Center Study in Korea
    Park, Hana
    Choi, Ki Hong
    Choi, Sae-Byeol
    Choi, Jong Won
    Kim, Do Young
    Ahn, Sang Hoon
    Kim, Kyung Sik
    Choi, Jin Sub
    Han, Kwang-Hyub
    Chon, Chae Yoon
    Park, Jun Yong
    YONSEI MEDICAL JOURNAL, 2011, 52 (05) : 753 - 760
  • [42] Combined hepatocellular-cholangiocarcinoma producing parathyroid hormone-related protein: report of a case
    Matsumoto, Michinori
    Wakiyama, Shigeki
    Shiba, Hiroaki
    Gocho, Takeshi
    Misawa, Takeyuki
    Ishida, Yuichi
    Itsubo, Mariko
    Suzuki, Masafumi
    Yanaga, Katsuhiko
    SURGERY TODAY, 2014, 44 (08) : 1577 - 1583
  • [43] Morphomolecular Pathology and Genomic Insights into the Cells of Origin of Cholangiocarcinoma and Combined Hepatocellular-Cholangiocarcinoma
    Guest, Rachel, V
    Goeppert, Benjamin
    Nault, Jean-Charles
    Sia, Daniela
    AMERICAN JOURNAL OF PATHOLOGY, 2025, 195 (03) : 345 - 361
  • [44] MRI features of combined hepatocellular-cholangiocarcinoma versus mass forming intrahepatic cholangiocarcinoma
    Sammon, Jennifer
    Fischer, Sandra
    Menezes, Ravi
    Hosseini-Nik, Hooman
    Lewis, Sara
    Taouli, Bachir
    Jhaveri, Kartik
    CANCER IMAGING, 2018, 18
  • [45] Case report: Toceranib as adjuvant chemotherapy in a dog with incompletely resected combined hepatocellular-cholangiocarcinoma
    Kim, Sang-Won
    Choi, Ju-Won
    Kim, Jeon-Mo
    Yoon, Hun-Young
    Bae, Kieun
    Yoon, Kyong-Ah
    Kim, Jung-Hyun
    FRONTIERS IN VETERINARY SCIENCE, 2023, 9
  • [46] Breast Metastasis From a Combined Hepatocellular-Cholangiocarcinoma
    Silva, Marco
    Coelho, Rosa
    Rios, Elisabete
    Gomes, Sara
    Carneiro, Fatima
    Macedo, Guilherme
    ACG CASE REPORTS JOURNAL, 2019, 6 (04)
  • [47] The Dominant Component and Clinicopathological Characteristics of Combined Hepatocellular-cholangiocarcinoma After Radical Resection
    Matsubara, Keiso
    Kobayashi, Tsuyoshi
    Tadokoro, Takeshi
    Namba, Yosuke
    Fukuhara, Sotaro
    Oshita, Ko
    Honmyo, Naruhiko
    Kuroda, Shintaro
    Arihiro, Koji
    Ohdan, Hideki
    ANTICANCER RESEARCH, 2024, 44 (10) : 4551 - 4559
  • [48] Combined hepatocellular-cholangiocarcinoma: biology, diagnosis, and management
    Ye, Liangtao
    Schneider, Julia S. S.
    Ben Khaled, Najib
    Schirmacher, Peter
    Seifert, Carolin
    Frey, Lea
    He, Yulong
    Geier, Andreas
    De Toni, Enrico N. N.
    Zhang, Changhua
    Reiter, Florian P. P.
    LIVER CANCER, 2024, 13 (01) : 6 - 28
  • [49] The significance of the predominant component in combined hepatocellular-cholangiocarcinoma: MRI manifestation and prognostic value
    Sheng, Ruofan
    Yang, Chun
    Zhang, Yunfei
    Wang, Heqing
    Zheng, Beixuan
    Han, Jing
    Sun, Wei
    Zeng, Mengsu
    RADIOLOGIA MEDICA, 2023, 128 (09): : 1047 - 1060
  • [50] Cytokeratin profiles and mucin secretion in combined hepatocellular-cholangiocarcinoma - A case report
    Hauben, E
    Struyf, N
    Michielsen, P
    VanMarck, E
    PATHOLOGY RESEARCH AND PRACTICE, 1996, 192 (05) : 488 - 491
12345