Integrated multilayer flow system on a microchip

被引：142

作者：

Hibara, A ^{[1
]}

Tokeshi, M

Uchiyama, K

Hisamoto, H

Kitamori, T

机构：

[1] Univ Tokyo, Sch Engn, Dept Appl Chem, Bunkyo Ku, Tokyo 1138656, Japan

[2] Kanagawa Acad Sci & Technol, Integrated Chem Project, Kawasaki, Kanagawa 2130012, Japan

来源：

ANALYTICAL SCIENCES | 2001年 / 17卷 / 01期

关键词：

D O I：

10.2116/analsci.17.89

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We utilized microchip technology and found that the multilayer flow of liquids can be formed in microchannels. Liquid/liquid interfaces were formed parallel to the side wall of the microchannels, because the surface tension and friction force are stronger than the force of gravity. A water/ethylacetate/water interface was formed in a 70-mum-wide and 30-mum-deep channel. The interface was observed to be quite stable and to be maintained for a distance of more than 18 cm. As an example of a multilayer flow application, we demonstrated the liquid/liquid extraction of Co-dimethylaminophenol complex in a microchannel. The solvent-extraction process of the complex into m-xylene in the multilayer flow was found to reach equilibrium in 4 s, while it took 60 s in a simple two-phase extraction.

引用

页码：89 / 93

页数：5

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