Genome-Wide Association Study for Glaucoma

被引：0
|
作者：
Liu, Jiang [1 ]
Zhang, Zhuo [1 ]
Chin, Shu Min [2 ]
Teo, Yun Lin Penny [2 ]
Wong, Wing Kee [1 ]
Tan, Ngan Meng [1 ]
Lim, Joo Hwee [1 ]
Lu, Shijian [1 ]
Li, Huiqi [1 ]
Wong, Tien Yin [3 ]
机构：
[1] ASTAR, Inst Infocomm Res, Singapore, Singapore
[2] Natl Univ Singapore, Singapore, Singapore
[3] Singapore Eye Res Inst, Singapore, Singapore
来源：
2009 INTERNATIONAL CONFERENCE ON BIOMEDICAL AND PHARMACEUTICAL ENGINEERING | 2009年
关键词：
SUSCEPTIBILITY; LOCI;
D O I：
暂无
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
The Genome-Wide Association (GWA) study is the latest approach in the development of genetic studies and is renowned for its widespread success in identifying disease variants within the genome for various common diseases. It is a highly popular study amongst geneticists worldwide, evident from the numerous GWA studies conducted in laboratories all over the world. This paper introduces various GWA study designs currently recognized, including other aspects such as the software tools and its progress thus far. Especially, the paper reviews the genetic studies for glaucoma, an ocular disease which can lead to irreversible and permanent vision loss. Glaucomatous progression can be slowed or even halted if detected early; however, genetic information on glaucoma has not been well established yet. Therefore, by conducting a GWA study on glaucoma to find comprehensive associated genetic variants, the early detection of glaucoma through GWA may finally be seen as a possibility.
引用
收藏
页码：162 / +
页数：3
相关论文
共 50 条
  • [21] A genome-wide association study for Kawasaki disease
    Hong, Mee Suk
    MOLECULAR & CELLULAR TOXICOLOGY, 2009, 5 (03) : 60 - 60
  • [22] Genome-Wide Association Study of Vascular Dementia
    Schrijvers, Elisabeth M. C.
    Schuermann, Britta
    Koudstaal, Peter J.
    van den Bussche, Hendrik
    Van Duijn, Cornelia M.
    Hentschel, Frank
    Heun, Reinhard
    Hofman, Albert
    Jessen, Frank
    Koelsch, Heike
    Kornhuber, Johannes
    Peters, Oliver
    Rivadeneira, Fernando
    Ruether, Eckart
    Uitterlinden, Andre G.
    Riedel-Heller, Steffi
    Dichgans, Martin
    Wiltfang, Jens
    Maier, Wolfgang
    Breteler, Monique M. B.
    Ikram, M. Arfan
    STROKE, 2012, 43 (02) : 315 - 319
  • [23] A Genome-Wide Association Study of Myasthenia Gravis
    Renton, Alan E.
    Pliner, Hannah A.
    Provenzano, Carlo
    Evoli, Amelia
    Ricciardi, Roberta
    Nalls, Michael A.
    Marangi, Giuseppe
    Abramzon, Yevgeniya
    Arepalli, Sampath
    Chong, Sean
    Hernandez, Dena G.
    Johnson, Janel O.
    Bartoccioni, Emanuela
    Scuderi, Flavia
    Maestri, Michelangelo
    Gibbs, J. Raphael
    Errichiello, Edoardo
    Chio, Adriano
    Restagno, Gabriella
    Sabatelli, Mario
    Macek, Mark
    Scholz, Sonja W.
    Corse, Andrea
    Chaudhry, Vinay
    Benatar, Michael
    Barohn, Richard J.
    McVey, April
    Pasnoor, Mamatha
    Dimachkie, Mazen M.
    Rowin, Julie
    Kissel, John
    Freimer, Miriam
    Kaminski, Henry J.
    Sanders, Donald B.
    Lipscomb, Bernadette
    Massey, Janice M.
    Chopra, Manisha
    Howard, James F., Jr.
    Koopman, Wilma J.
    Nicolle, Michael W.
    Pascuzzi, Robert M.
    Pestronk, Alan
    Wulf, Charlie
    Florence, Julaine
    Blackmore, Derrick
    Soloway, Aimee
    Siddiqi, Zaeem
    Muppidi, Srikanth
    Wolfe, Gil
    Richman, David
    JAMA NEUROLOGY, 2015, 72 (04) : 396 - 404
  • [24] Genome-wide association study of citrus microbiome
    Xu, J.
    Wang, N.
    PHYTOPATHOLOGY, 2021, 111 (10) : 13 - 13
  • [25] GENOME-WIDE ASSOCIATION STUDY OF INSOMNIA PHENOTYPES
    Gehrman, P.
    Byrne, E. M.
    Martin, N. G.
    Wray, N. R.
    SLEEP, 2011, 34 : A12 - A12
  • [26] Genome-wide association study of selenium concentrations
    Cornelis, Marilyn C.
    Fornage, Myriam
    Foy, Millennia
    Xun, Pengcheng
    Gladyshev, Vadim N.
    Morris, Steve
    Chasman, Daniel I.
    Hu, Frank B.
    Rimm, Eric B.
    Kraft, Peter
    Jordan, Joanne M.
    Mozaffarian, Dariush
    He, Ka
    HUMAN MOLECULAR GENETICS, 2015, 24 (05) : 1469 - 1477
  • [27] A genome-wide association study for subjective wellbeing
    Bartels, Meike
    de Geus, Eco
    Groen-Blokhuis, Maria
    de Moor, Marleen
    van Beijsterveldt, Toos
    Hottenga, Jouke-Jan
    Ehli, Erik
    Davies, Gareth
    Xiang, Xiao
    Scheet, Paul
    Hudziak, Jim
    Boomsma, Dorret
    BEHAVIOR GENETICS, 2011, 41 (06) : 892 - 892
  • [28] Alopecia Areata genome-wide association study
    Petukhova, L.
    Ripke, S.
    Becker, T.
    Duvic, M.
    Hordinsky, M.
    Norris, D.
    Price, V.
    Mackay-Wiggan, J.
    Redler, S.
    Chen, W. V.
    Amos, C. I.
    Lee, A.
    Gregersen, P. K.
    Blaumeiser, B.
    Altshuler, D.
    Daly, M. J.
    Noethen, M.
    Betz, R.
    Christiano, A. M.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2012, 132 : S73 - S73
  • [29] GENOME-WIDE ASSOCIATION STUDY OF ADOLESCENTONSET DEPRESSION
    Grimes, Poppy
    Adams, Mark
    Thapar, Anita
    Middeldorp, Christel M.
    McIntosh, Andrew
    Whalley, Heather
    Kwong, Alex S. F.
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2024, 87 : 37 - 37
  • [30] A GENOME-WIDE ASSOCIATION STUDY PRIMER FOR CLINICIANS
    Wang, Tzu-Hao
    Wang, Hsin-Shih
    TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY, 2009, 48 (02): : 89 - 95
12345