FcεRI- and MRGPRX2-evoked acute degranulation responses are fully additive in human skin mast cells

被引:23
作者
Babina, Magda [1 ,2 ,3 ,4 ,5 ]
Wang, Zhao [1 ,2 ,3 ,4 ,6 ]
Li, Zhuoran [1 ,2 ,3 ,4 ,5 ]
Franke, Kristin [1 ,2 ,3 ,4 ,5 ]
Guhl, Sven [1 ,2 ,3 ,4 ,5 ]
Artuc, Metin [1 ,2 ,3 ,4 ,5 ]
Zuberbier, Torsten [1 ,2 ,3 ,4 ,5 ]
机构
[1] Charite Univ Med Berlin, Inst Allergol, Berlin, Germany
[2] Free Univ Berlin, Berlin, Germany
[3] Humboldt Univ, Berlin, Germany
[4] Berlin Inst Hlth, Berlin, Germany
[5] Fraunhofer Inst Translat Med & Pharmacol ITMP All, Berlin, Germany
[6] Xi An Jiao Tong Univ, Northwest Hosp, Affiliated Hosp 2, Dept Dermatol, Xian, Peoples R China
关键词
anaphylaxis; drug allergy; Fc epsilon RI; mast cell; MRGPRX2;
D O I
10.1111/all.15270
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:1906 / 1909
页数:4
相关论文
共 7 条
  • [1] Allergic FcεRI- and pseudo-allergic MRGPRX2-triggered mast cell activation routes are independent and inversely regulated by SCF
    Babina, M.
    Guhl, S.
    Artuc, M.
    Zuberbier, T.
    [J]. ALLERGY, 2018, 73 (01) : 256 - 260
  • [2] Babina M., 2020, Itch, V5, P32, DOI [DOI 10.1097/ITX.0000000000000032, 10.1097/itx.0000000000000032]
  • [3] MRGPRX2 Is the Codeine Receptor of Human Skin Mast Cells: Desensitization through β-Arrestin and Lack of Correlation with the FcεRI Pathway
    Babina, Magda
    Wang, Zhao
    Roy, Saptarshi
    Guhl, Sven
    Franke, Kristin
    Artuc, Metin
    Ali, Hydar
    Zuberbier, Torsten
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2021, 141 (05) : 1286 - +
  • [4] MRGPRX2 is negatively targeted by SCF and IL-4 to diminish pseudo-allergic stimulation of skin mast cells in culture
    Babina, Magda
    Wang, Zhao
    Artuc, Metin
    Guhl, Sven
    Zuberbier, Torsten
    [J]. EXPERIMENTAL DERMATOLOGY, 2018, 27 (11) : 1298 - 1303
  • [5] Different activation signals induce distinct mast cell degranulation strategies
    Gaudenzio, Nicolas
    Sibilano, Riccardo
    Marichal, Thomas
    Starkl, Philipp
    Reber, Laurent L.
    Cenac, Nicolas
    McNeil, Benjamin D.
    Dong, Xinzhong
    Hernandez, Joseph D.
    Sagi-Eisenberg, Ronit
    Hammel, Ilan
    Roers, Axel
    Valitutti, Salvatore
    Tsai, Mindy
    Espinosa, Eric
    Galli, Stephen J.
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2016, 126 (10) : 3981 - 3998
  • [6] MRGPRX2 and Adverse Drug Reactions
    McNeil, Benjamin D.
    [J]. FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [7] The pseudoallergen receptor MRGPRX2 on peripheral blood basophils and eosinophils: Expression and function
    Wedi, Bettina
    Gehring, Manuela
    Kapp, Alexander
    [J]. ALLERGY, 2020, 75 (09) : 2229 - 2242