The Physiology of Proinsulin C-Peptide: Unanswered Questions and a Proposed Model

被引：20
|
作者：
Yosten, Gina L. C. [1 ]
Kolar, Grant R. [2 ]
机构：
[1] St Louis Univ, Sch Med, Dept Pharmacol & Physiol Sci, St Louis, MO 63104 USA
[2] St Louis Univ, Sch Med, Dept Pathol, St Louis, MO 63104 USA
来源：
PHYSIOLOGY | 2015年 / 30卷 / 04期
关键词：
O-2-INDUCED ATP RELEASE; PROTEIN-KINASE-C; RECEPTOR; INSULIN; BINDING; COMPLICATIONS; DYSFUNCTION; ALPHA; CELLS; ERYTHROCYTES;
D O I：
10.1152/physiol.00008.2015
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
C-peptide is produced, processed, and secreted with insulin, and appears to exert separate but intimately related effects. In this review, we address the existence of the C-peptide receptor, the interaction between C-peptide and insulin, and the potential physiological significance of proinsulin C-peptide.
引用
收藏
页码：327 / 332
页数：6
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