Osteoarticular infections in pediatrics

被引:26
作者
Alvares, Paula Andrade [1 ]
Mimica, Marcelo Jenne [2 ,3 ]
机构
[1] Santa Casa Sao Paulo, Dept Pediat, Sao Paulo, SP, Brazil
[2] Santa Casa Sao Paulo, Setor Infectol Pediat, Dept Pediat, Sao Paulo, SP, Brazil
[3] Fac Ciencias Med Santa Casa Sao Paulo, Dept Ciencias Patol, Disciplina Microbiol, Sao Paulo, SP, Brazil
关键词
Osteoarticular; Infections; Children; S; aureus; pyogenes; ACUTE HEMATOGENOUS OSTEOMYELITIS; SEPTIC ARTHRITIS; JOINT INFECTIONS; KINGELLA-KINGAE; BONE; CHILDREN; EPIDEMIOLOGY;
D O I
10.1016/j.jped.2019.10.005
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Objective: To collect the most up-to-date information regarding pediatric osteoarticular infections, including the epidemiological and microbiological profiles, diagnosis, and treatment. Source of data: A non-systematic review was performed on the search engines PubMed, SciELO, Lilacs, and Google Scholar, using the keywords "bone and joint infection", "children", "pediatric", "osteomyelitis", "septic arthritis" and "spondylodiscitis" over the last ten years. The most relevant articles were selected by the authors to constitute the database. Synthesis of data: Osteoarticular infections are still a major cause of morbidity in pediatrics. Their main etiology is Staphylococcus aureus, but there has been an increase in the detection of Kingella kingae, especially through molecular methods. Microbiological identification allows treatment direction, while evidence of inflammatory activity assists in treatment follow-up. Imaging tests are especially useful in the initial diagnosis of infections. Empirical treatment should include coverage for the main microorganisms according to the age and clinical conditions of the patient, while considering the local resistance profile. Surgical procedures can be indicated for diagnosis, focus control, and function preservation. Acute complications include sepsis, deep venous thrombosis, and pulmonary embolism. Deaths are rare. Late complications are uncommon but may lead to deformities that compromise motor development. Conclusion: A correct and early diagnosis, prompt implementation of adequate antimicrobial therapy, and focus control, when indicated, are critical to a better prognosis. (C) 2019 Published by Elsevier Editora Ltda. on behalf of Sociedade Brasileira de Pediatria.
引用
收藏
页码:58 / 64
页数:7
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