A study of eukaryotic response mechanisms to atmospheric pressure cold plasma by using Saccharomyces cerevisiae single gene mutants

被引：31

作者：

Feng, Hongqing ^{[1
]}

Wang, Ruixue ^{[1
]}

Sun, Peng ^{[2
]}

Wu, Haiyan ^{[2
]}

Liu, Qi ^{[1
,3
]}

Fang, Jing ^{[1
,2
]}

Zhu, Weidong

Li, Fangting ^{[1
,3
]}

Zhang, Jue ^{[1
,2
]}

机构：

[1] Peking Univ, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China

[2] Peking Univ, Coll Engn, Beijing 100871, Peoples R China

[3] Peking Univ, Coll Phys, Beijing 100871, Peoples R China

来源：

APPLIED PHYSICS LETTERS | 2010年 / 97卷 / 13期

关键词：

CELL-CYCLE; AIR PLASMA; YEAST; INACTIVATION; TRANSCRIPTION; ENVIRONMENT; BACTERIA;

D O I：

10.1063/1.3491180

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

The mechanisms of eukaryotic cell response to cold plasma are studied. A series of single gene mutants of eukaryotic model organism Saccharomyces cerevisiae are used to compare their sensitivity to plasma treatment with the wild type. We examined 12 mutants in the oxidative stress pathway and the cell cycle pathway, in which 8 are found to be hypersensitive to plasma processing. The mutated genes' roles in the two pathways are analyzed to understand the biological response mechanisms of plasma treatment. The results demonstrate that genes from both pathways are needed for the eukaryotic cells to survive the complex plasma treatment. (C) 2010 American Institute of Physics. [doi: 10.1063/1.3491180]

引用

页数：3

共 25 条

[1] [Anonymous], 2007, SACCHAROMYCES GENOME
[2] Sensing the environment: lessons from fungi
Bahn, Yong-Sun
Xue, Chaoyang
Idnurm, Alexander
Rutherford, Julian C.
Heitman, Joseph
Cardenas, Maria E.
[J]. NATURE REVIEWS MICROBIOLOGY, 2007, 5 (01) : 57 - 69
[3] Ask10p mediates the oxidative stress-induced destruction of the Saccharomyces cerevisiae C-type cyclin Ume3p/Srb11p
Cohen, TJ
Lee, K
Rutkowski, LH
Strich, R
[J]. EUKARYOTIC CELL, 2003, 2 (05) : 962 - 970
[4] Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae
Enserink, Jorrit M.
Hombauer, Hans
Huang, Meng-Er
Kolodner, Richard D.
[J]. JOURNAL OF CELL BIOLOGY, 2009, 185 (03) : 423 - 437
[5] The Interaction of a Direct-Current Cold Atmospheric-Pressure Air Plasma With Bacteria
Feng, Hongqing
Sun, Peng
Chai, Yufeng
Tong, Guohua
Zhang, Jue
Zhu, Weidong
Fang, Jing
[J]. IEEE TRANSACTIONS ON PLASMA SCIENCE, 2009, 37 (01) : 121 - 127
[6] FRIDMAN A, 2007, P INT C PLASM MED IC
[7] ELECTRON-SPIN RESONANCE STUDY OF SPIN ADDUCTS OF OH AND HO2 RADICALS WITH NITRONES IN ULTRAVIOLET PHOTOLYSIS OF AQUEOUS HYDROGEN-PEROXIDE SOLUTIONS
HARBOUR, JR
CHOW, V
BOLTON, JR
[J]. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1974, 52 (20): : 3549 - 3553
[8] SINGLET OXYGEN PRODUCTION IN THYLAKOID MEMBRANES DURING PHOTOINHIBITION AS DETECTED BY EPR SPECTROSCOPY
HIDEG, E
SPETEA, C
VASS, I
[J]. PHOTOSYNTHESIS RESEARCH, 1994, 39 (02) : 191 - 199
[9] Effects of pH on Bacterial Inactivation in Aqueous Solutions due to Low-Temperature Atmospheric Pressure Plasma Application
Ikawa, Satoshi
Kitano, Katsuhisa
Hamaguchi, Satoshi
[J]. PLASMA PROCESSES AND POLYMERS, 2010, 7 (01) : 33 - 42
[10] Yeast signaling pathways in the oxidative stress response
Ikner, A
Shiozaki, K
[J]. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2005, 569 (1-2) : 13 - 27

← 1 2 3 →