A study of eukaryotic response mechanisms to atmospheric pressure cold plasma by using Saccharomyces cerevisiae single gene mutants

被引：32

作者：

Feng, Hongqing ^{[1
]}

Wang, Ruixue ^{[1
]}

Sun, Peng ^{[2
]}

Wu, Haiyan ^{[2
]}

Liu, Qi ^{[1
,3
]}

Fang, Jing ^{[1
,2
]}

Zhu, Weidong

Li, Fangting ^{[1
,3
]}

Zhang, Jue ^{[1
,2
]}

机构：

[1] Peking Univ, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China

[2] Peking Univ, Coll Engn, Beijing 100871, Peoples R China

[3] Peking Univ, Coll Phys, Beijing 100871, Peoples R China

来源：

APPLIED PHYSICS LETTERS | 2010年 / 97卷 / 13期

关键词：

CELL-CYCLE; AIR PLASMA; YEAST; INACTIVATION; TRANSCRIPTION; ENVIRONMENT; BACTERIA;

D O I：

10.1063/1.3491180

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

The mechanisms of eukaryotic cell response to cold plasma are studied. A series of single gene mutants of eukaryotic model organism Saccharomyces cerevisiae are used to compare their sensitivity to plasma treatment with the wild type. We examined 12 mutants in the oxidative stress pathway and the cell cycle pathway, in which 8 are found to be hypersensitive to plasma processing. The mutated genes' roles in the two pathways are analyzed to understand the biological response mechanisms of plasma treatment. The results demonstrate that genes from both pathways are needed for the eukaryotic cells to survive the complex plasma treatment. (C) 2010 American Institute of Physics. [doi: 10.1063/1.3491180]

引用

页数：3

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