Studies on marine toxins: chemical and biological aspects

被引:4
|
作者
Stonik, V. A. [1 ]
Stonik, I. V. [2 ]
机构
[1] Russian Acad Sci, Pacific Inst Bioorgan Chem, Far Eastern Branch, Vladivostok 690022, Russia
[2] Russian Acad Sci, AV Zhirmunsky Inst Marine Biol, Far Eastern Branch, Vladivostok 690041, Russia
关键词
PARALYTIC SHELLFISH TOXINS; PROPOSED AZASPIRACID-1 STRUCTURE; JAPANESE IVORY SHELL; OKADAIC ACID; LIQUID-CHROMATOGRAPHY; DOMOIC ACID; ABSOLUTE-CONFIGURATION; STEREOCHEMICAL ASSIGNMENT; ALEXANDRIUM-TAMARENSE; CONVERGENT STRATEGIES;
D O I
10.1070/RC2010v079n05ABEH004105
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The structures and mechanisms of biological action of the best known representatives of the main groups of marine toxins are presented. It is shown that many compounds have complex chemical structures and possess extremely high toxicities. Characteristic features of isolation, structure determination and syntheses of these compounds using the achievement of modern organic chemistry are discussed. The methods of identification and quantitative analysis of marine toxins are briefly reviewed. The bibliography includes 147 reference.
引用
收藏
页码:397 / 419
页数:23
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