Lysosomal pH and analysis of the counter ion pathways that support acidification

被引：79

作者：

DiCiccio, Jessica E. ^{[1
,2
]}

Steinberg, Benjamin E. ^{[1
,3
]}

机构：

[1] Hosp Sick Children, Cell Biol Program, Toronto, ON M5G 1X8, Canada

[2] Univ Toronto, Dept Biochem, Toronto, ON M5S 1A8, Canada

[3] Univ Toronto, Fac Med, Toronto, ON M5S 1A8, Canada

来源：

JOURNAL OF GENERAL PHYSIOLOGY | 2011年 / 137卷 / 04期

基金：

加拿大健康研究院;

关键词：

TRANSMEMBRANE CONDUCTANCE REGULATOR; CYSTIC-FIBROSIS; STORAGE DISEASE; CLC PROTEINS; MACROPHAGES; OSTEOPETROSIS; ACCUMULATION; ENDOCYTOSIS; PHYSIOLOGY; PATHOLOGY;

D O I：

10.1085/jgp.201110596

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

[No abstract available]

引用

页码：385 / 390

页数：6

共 27 条

[1] Revisiting the Role of Cystic Fibrosis Transmembrane Conductance Regulator and Counterion Permeability in the pH Regulation of Endocytic Organelles [J].

Barriere, Herve ;

Bagdany, Miklos ;

Bossard, Florian ;

Okiyoneda, Tsukasa ;

Wojewodka, Gabriella ;

Gruenert, Dieter ;

Radzioch, Danuta ;

Lukacs, Gergely L. .

MOLECULAR BIOLOGY OF THE CELL, 2009, 20 (13) :3125-3141

[2]

Christensen KA, 2002, J CELL SCI, V115, P599

[3] Disease-causing Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator Determine the Functional Responses of Alveolar Macrophages [J].

Deriy, Ludmila V. ;

Gomez, Erwin A. ;

Zhang, Guangping ;

Beacham, Daniel W. ;

Hopson, Jessika A. ;

Gallan, Alexander J. ;

Shevchenko, Pavel D. ;

Bindokas, Vytautas P. ;

Nelson, Deborah J. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (51) :35926-35938

[4] CFTR regulates phagosome acidification in macrophages and alters bactericidal activity [J].

Di, Anke ;

Brown, Mary E. ;

Deriy, Ludmila V. ;

Li, Chunying ;

Szeto, Frances L. ;

Chen, Yimei ;

Huang, Ping ;

Tong, Jiankun ;

Naren, Anjaparavanda P. ;

Bindokas, Vytautas ;

Palfrey, H. Clive ;

Nelson, Deborah J. .

NATURE CELL BIOLOGY, 2006, 8 (09) :933-U52

[5] Mechanisms of Endocytosis [J].

Doherty, Gary J. ;

McMahon, Harvey T. .

ANNUAL REVIEW OF BIOCHEMISTRY, 2009, 78 :857-902

[6] Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology [J].

Forgac, Michoel .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2007, 8 (11) :917-929

[7] The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes [J].

Graves, Austin R. ;

Curran, Patricia K. ;

Smith, Carolyn L. ;

Mindell, Joseph A. .

NATURE, 2008, 453 (7196) :788-792

[8] Cystic fibrosis transmembrane conductance regulator-independent phagosomal acidification in macrophages [J].

Haggie, Peter M. ;

Verkman, A. S. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (43) :31422-31428

[9] Unimpaired Lysosomal Acidification in Respiratory Epithelial Cells in Cystic Fibrosis [J].

Haggie, Peter M. ;

Verkman, A. S. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (12) :7681-7686

[10]

Jentsch TJ, 2008, CRIT REV BIOCHEM MOL, V43, P3, DOI [10.1080/10409230701829110, 10.1080/10409230701829110 ]

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