Cutaneous Leishmaniasis (Leishmania major Infection) in Dutch Troops Deployed in Northern Afghanistan: Epidemiology, Clinical Aspects, and Treatment

被引：43

作者：

van Thiel, Pieter-Paul ^{[1
,2
,3
]}

Leenstra, Tjalling ^{[1
,2
,3
]}

de Vries, Henry J. ^{[4
]}

van der Sluis, Allard ^{[3
]}

van Gool, Tom ^{[5
]}

Krull, Alex C. ^{[1
,2
,3
]}

van Vugt, Michele ^{[1
,2
,6
]}

de Vries, Peter J. ^{[1
,2
]}

Zeegelaar, Jimmy E. ^{[4
,7
]}

Bart, Aldert ^{[5
]}

van der Meide, Wendy F. ^{[8
]}

Schallig, Henk D. F. H. ^{[9
]}

Faber, William R.

Kager, Piet A. ^{[1
,2
]}

机构：

[1] Univ Amsterdam, Dept Internal Med, Div Infect Dis Trop Med & AIDS, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands

[2] Univ Amsterdam, Ctr Infect & Immun, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands

[3] Netherlands Minist Def, The Hague, Netherlands

[4] Univ Amsterdam, Dept Dermatol, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands

[5] Univ Amsterdam, Dept Med Microbiol, Acad Med Ctr, Sect Parasitol, NL-1105 AZ Amsterdam, Netherlands

[6] PharmAccess Fdn, Amsterdam, Netherlands

[7] Flevoziekenhuis, Dept Dermatol, Almere, Netherlands

[8] U Cytech Biosci, Utrecht, Netherlands

[9] Koninklijk Inst Tropen, Royal Trop Inst, KIT Biomed Res, Parasitol Unit, Amsterdam, Netherlands

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2010年 / 83卷 / 06期

关键词：

DISSEMINATION; SEQUENCE; SAMPLES; TURKEY; KABUL; TOOL;

D O I：

10.4269/ajtmh.2010.10-0143

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Cutaneous leishmaniasis caused by Leishmania major infection affected 172 (18.3%) of 938 Dutch military troops deployed in northern Afghanistan in 2005. The high attack rate was a result of initial insufficient availability of means of prevention and insufficient adherence to preventive measures. At presentation, the lymphatic system was involved in 24.8%. Treatment with intralesional injections of antimony with or without cryotherapy was satisfactory, but 19.5% of patients received secondary treatment with miltefosine. Six months after treatment, 128 (77.1%) of 166 treated patients were cured, 16 (9.6%) were lost to follow-up, and 22 (13.3%) already experienced cure at six weeks but were not seen at six months. Natural evolution played a role in this observational study, which showed cure of all patients seen at six months. In general, management of cutaneous leishmaniasis was feasible under field conditions.

引用

页码：1295 / 1300

页数：6

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