Dinucleosomes show compaction by ionic strength, consistent with bending of linker DNA

被引：33

作者：

Butler, PJG

Thomas, JO

机构：

[1] Cambridge Ctr Mol Recognit, Cambridge CB2 1GA, England

[2] Dept Biochem, Cambridge CB2 1GA, England

[3] MRC, Mol Biol Lab, Cambridge CB2 2QH, England

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1998年 / 281卷 / 03期

基金：

英国生物技术与生命科学研究理事会;

关键词：

chromatin; dinucleosomes; linker DNA; sedimentation; DNA bending;

D O I：

10.1006/jmbi.1998.1954

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nucleosome dimers from chicken erythrocytes show an ionic strength dependence of sedimentation coefficient similar to that of trimers, and indicative of a degree of compaction over a range of low ionic strengths. This is not easily reconciled with straight linkers but is consistent with bending or kinking of the linker DNA. (C) 1998 Academic Press.

引用

页码：401 / 407

页数：7

共 37 条

[1] PARTICIPATION OF CORE HISTONE TAILS IN THE STABILIZATION OF THE CHROMATIN SOLENOID [J].