Synthesis of some new bioactive 1-N-subtituted 3,5-diaryl-2-pyrazolines

被引：0

作者：

Khan, Sadaf Sadiq ^{[1
]}

Hasan, Aurangzeb ^{[1
]}

机构：

[1] Quaid i Azam Univ, Dept Chem, Islamabad 45320, Pakistan

来源：

HETEROCYCLIC COMMUNICATIONS | 2007年 / 13卷 / 2-3期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A group of four series (A-D) of 22 new bioactive 1-N-acid substituted 3, 5-diphenyl-2-pyrazolines were synthesized by cyclization of variably substituted chalcones and simple or substituted phenyl hydrazine and / or semicarbazide, using acetic acid as a solvent. The chemical structure of the compounds was characterized by FTIR, (HNMR)-H-1, and EIMS spectroscopy and chemical analyses. The antifungal and antibacterial activities of these compounds were evaluated by agar tube dilution method and agar well diffusion method respectively.

引用

页码：131 / 138

页数：8

共 25 条

[1] Abdou N A, 1993, B FAC PHARM, V31, P361
[2] Acheson RM, 1976, INTRO CHEM HETEROCYC
[3] [Anonymous], 1995, CHEM HETEROCYCLES
[4] BADGER GM, 1961, CHEM HETEROCYCLES
[5] Convergent synthesis and antibacterial activity of pyrazole and pyrazoline derivatives of diazepam
Berghot, MA
Moawad, EB
[J]. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2003, 20 (02) : 173 - 179
[6] SENSITIVITY OF SOME PLANT PATHOGENIC FUNGI TOWARDS PLANT METABOLITES - ANTIFUNGAL ACTIVITY OF SOME CHALCONES, DIHYDROCHALCONES AND FLAVANONES
CHOWDHUR.A
MUKHERJE.N
ADITYACH.N
[J]. EXPERIENTIA, 1974, 30 (09): : 1022 - 1024
[7] DAWEY W, 1958, J CHEM SOC, V24, P1320
[8] ELHASHASH MA, 1995, REV ROUM CHIM, V40, P59
[9] GABOR M, 1967, ACTA MICROBIOL HUNG, V14, P45
[10] IEVEN M, 1979, PLANTA MED, V36, P311

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