Effectiveness of BNT162b2 COVID-19 Vaccine in Preventing Severe Symptomatic Infection among Healthcare Workers

被引：7

作者：

Murillo-Zamora, Efren ^{[1
,2
]}

Trujillo, Xochitl ^{[3
]}

Huerta, Miguel ^{[3
]}

Rios-Silva, Monica ^{[3
]}

Mendoza-Cano, Oliver ^{[4
]}

机构：

[1] Inst Mexicano Seguro Social, Dept Epidemiol, Unidad Med Familiar 19, Av Javier Mina 301, Colima 28000, Mexico

[2] Univ Colima, Fac Med, Av Univ 333, Colima 28040, Mexico

[3] Univ Colima, Ctr Univ Invest Biomed, Av 25 Julio 965, Colima 28045, Mexico

[4] Univ Colima, Fac Ingn Civil, Km 9 Carretera Colima Coquimatlan, Colima 28400, Mexico

来源：

MEDICINA-LITHUANIA | 2021年 / 57卷 / 08期

关键词：

COVID-19; vaccines; BNT162; vaccine; SARS-COV-2;

D O I：

10.3390/medicina57080746

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background and Objectives: This study aims to evaluate the effectiveness of the BNT162b2 COVID-19 (coronavirus disease 2019) in preventing severe symptomatic laboratory-confirmed infection among healthcare workers in a real-world scenario. Materials and Methods: A cross-sectional analysis of a prospective cohort study was conducted. Subjects with onset illness from January to February 2021 were eligible and classified according to the number of vaccine doses received (single-shot, n = 8; two-shot, n = 12; unvaccinated, n = 290). Results: The vaccine effectiveness against severe illness was 100% in the single and two-shot group. The presented results suggest that vaccination reduces the frequency of severe symptomatic COVID-19 in working-age adults. Conclusions: Efforts focusing on maximizing the number of immunized subjects in the study population may reduce associated economic and social burdens.

引用

页数：4

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