Indications for and outcome of antidepressant medication in a general population:: a prescription database and medical record study, in Jamtland county, Sweden, 1995

被引：43
作者：
Henriksson, S
Boëthius, G
Håkansson, J
Isacsson, G
机构：
[1] Karolinska Inst, Huddinge Univ Hosp, Div Psychiat, NEUROTEC, Stockholm, Sweden
[2] Ostersund Hosp, Tobacco Control Unit, Ostersund, Sweden
[3] Krokom Hlth Ctr, Krokom, Sweden
来源：
ACTA PSYCHIATRICA SCANDINAVICA | 2003年 / 108卷 / 06期
关键词：
depression; antidepressive agents (tricyclics; second generation); treatment outcome; pharmacoepidemiology;
D O I：
10.1046/j.0001-690X.2003.00166.x
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Objective: To examine the indications for prescribing antidepressants and the clinical outcome when they are prescribed for the treatment of depression, and compare tricyclic antidepressants (TCAs) and selective serotonin re-uptake inhibitors (SSRIs) in these respects. Method: A naturalistic study of a prospective prescription monitoring database and medical records. Results: Depression was the indication for 23% of the tricyclic treatments and for 82% of the SSRI treatments. A successful treatment of the depression was found in 20% of the TCA cases and 41% of the SSRI cases (NS). Conclusion: This study provides evidence that the main use of SSRIs in 1995 is the treatment of depression. The study implies that SSRIs have a more favourable outcome in 'real life' than TCAs.
引用
收藏
页码：427 / 431
页数：5
相关论文
共 20 条
[1]   Psychopharmacological treatment and psychiatric morbidity in 390 cases of suicide with special focus on affective disorders [J].
Andersen, UA ;
Anderson, M ;
Rosholm, JU ;
Gram, LF .
ACTA PSYCHIATRICA SCANDINAVICA, 2001, 104 (06) :458-465
[2]   Paroxetine and its uses in psychiatry [J].
Bell, C ;
Nutt, D .
HOSPITAL MEDICINE, 1999, 60 (05) :353-356
[3]   Which patients receive antidepressants? A 'real world' telephone study [J].
Bouhassira, M ;
Allicar, MP ;
Blachier, C ;
Nouveau, A ;
Rouillon, F .
JOURNAL OF AFFECTIVE DISORDERS, 1998, 49 (01) :19-26
[4]   Antidepressant drug use: Differences between psychiatrists and general practitioners - Results from a drug utilization observation study with fluoxetine [J].
Dittmann, RW ;
Linden, M ;
Osterheider, M ;
Schaaf, B ;
Ohnmacht, U ;
Weber, HJ .
PHARMACOPSYCHIATRY, 1997, 30 :28-34
[5]  
DONAGHUE JM, 1996, BRIT J PSYCHIAT, V168, P164
[6]   Suicides are seldom prescribed antidepressants:: findings from a prospective prescription database in Jamtland county, Sweden, 1985-95 [J].
Henriksson, S ;
Boëthius, G ;
Isacsson, G .
ACTA PSYCHIATRICA SCANDINAVICA, 2001, 103 (04) :301-306
[7]   Selective serotonin reuptake inhibitors have broadened the utilisation of antidepressant treatment in accordance with recommendations -: Findings from Swedish prescription database [J].
Isacsson, G ;
Boëthius, G ;
Henriksson, S ;
Jones, JK ;
Bergman, U .
JOURNAL OF AFFECTIVE DISORDERS, 1999, 53 (01) :15-22
[8]   Suicide prevention - a medical breakthrough? [J].
Isacsson, G .
ACTA PSYCHIATRICA SCANDINAVICA, 2000, 102 (02) :113-117
[9]   Regular review - Management of patients who deliberately harm themselves [J].
Isacsson, G ;
Rich, CL .
BMJ-BRITISH MEDICAL JOURNAL, 2001, 322 (7280) :213-215
[10]   Antidepressant treatment of depression in the Finnish general population [J].
Laukkala, T ;
Isometsä, E ;
Hämäläinen, J ;
Heikkinen, M ;
Lindeman, S ;
Aro, H .
AMERICAN JOURNAL OF PSYCHIATRY, 2001, 158 (12) :2077-2079
12