Synthesis of 9-Fluorenylidenes via Pd-Catalyzed C-H Vinylation with Vinyl Bromides

被引：13
作者：
Yang, Shuai [1 ]
Zhang, Yanghui [1 ]
机构：
[1] Tongji Univ, Shanghai Key Lab Chem Assessment & Sustainabil, Sch Chem Sci & Engn, Shanghai 200092, Peoples R China
来源：
ORGANIC LETTERS | 2021年 / 23卷 / 20期
基金：
中国国家自然科学基金;
关键词：
COUPLING REACTIONS; METHOXY GROUPS; BOND; ACTIVATION; FUNCTIONALIZATION; CONFORMATION; DERIVATIVES; ANNULATION; FLUORENES; INSERTION;
D O I：
10.1021/acs.orglett.1c02722
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile and efficient approach for the synthesis of 9-fluorenylidenes has been developed via the palladium-catalyzed cross-coupling of 2-iodobiphenyls and vinyl bromides. The reaction involves the C-H activation of 2-iodobiphenyls and dual C-C bond formations. A range of 9-fluorenylidene derivatives, including diphenyldibenzofulvenes, can be synthesized with the reaction.
引用
收藏
页码：7746 / 7750
页数：5
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