Case report of eight pregnant women with syphilis

被引：2

作者：

Nakasuji, Yukiko ^{[1
]}

Tanimura, Kenji ^{[1
]}

Sasagawa, Yuki ^{[1
]}

Imafuku, Hitomi ^{[1
]}

Morizane, Mayumi ^{[1
]}

Fujioka, Kazumichi ^{[2
]}

Ohji, Goh ^{[3
]}

Yamada, Hideto ^{[1
]}

机构：

[1] Kobe Univ, Dept Obstet & Gynecol, Grad Sch Med, Kobe, Hyogo, Japan

[2] Kobe Univ, Dept Pediat, Grad Sch Med, Kobe, Hyogo, Japan

[3] Kobe Univ, Dept Infect Dis & Microbiol, Grad Sch Med, Kobe, Hyogo, Japan

来源：

JOURNAL OF INFECTION AND CHEMOTHERAPY | 2020年 / 26卷 / 03期

关键词：

Amoxicillin; Congenital syphilis; Penicillin G; Pregnancy; Syphilis;

D O I：

10.1016/j.jiac.2019.10.016

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Congenital syphilis may lead to severe sequelae in affected infants. The prevalence of syphilis in women of childbearing age has increased worldwide. From 2015 to 2018, we encountered eight pregnant women with syphilis including six with late latent and two with early latent syphilis. Seven pregnant women with syphilis received antibiotic therapies of oral amoxicillin, intravenous penicillin G, or the both. The syphilotherapies in four cases were considered effective, because rapid plasma reagin titers decreased. None of the seven pregnant women who received syphilotherapies had congenital syphilis. The remaining one woman who did not undergo a maternity checkup or syphilotherapy delivered a stillbirth with congenital syphilis at 29 gestational weeks. (c) 2019 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

引用

页码：298 / 300

页数：3

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