Probing Mechanical Characteristics of Living Fibroblasts via Atomic Force Microscopy

被引：6

作者：

Timoshchuk, K. I. ^{[1
]}

Khalisov, M. M. ^{[1
]}

Penniyaynen, V. A. ^{[1
]}

Krylov, B. V. ^{[1
]}

Ankudinov, A. V. ^{[2
]}

机构：

[1] Russian Acad Sci, Pavlov Inst Physiol, St Petersburg 199034, Russia

[2] Russian Acad Sci, Ioffe Phys Tech Inst, St Petersburg 194021, Russia

来源：

TECHNICAL PHYSICS LETTERS | 2019年 / 45卷 / 09期

基金：

俄罗斯基础研究基金会;

关键词：

atomic force microscopy; fibroblasts; colchicine; CELLS;

D O I：

10.1134/S1063785019090293

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

Atomic force microscopy (AFM) measurements have revealed hardening of intact fibroblasts after treatment with colchicine. The reliability of AFM measurements was confirmed by the identification of cells the lateral response of which to indentation did not disturb the normal force contribution. AFM data on the mechanical characteristics of such cells admit an unambiguous interpretation.

引用

页码：947 / 950

页数：4

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