Synthesis of Trifluoromethyl-Substituted Fused Bicyclic Heterocycles and their Corresponding Benzo-Fused Analogues

被引：43

作者：

Elwahy, Ahmed H. M. ^{[1
,2
]}

Shaaban, Mohamed R. ^{[1
,2
]}

机构：

[1] Cairo Univ, Dept Chem, Fac Sci, Giza, Egypt

[2] Umm Al Qura Univ, Fac Sci Appl, Dept Chem, Makkah Alumukkarramah, Saudi Arabia

来源：

CURRENT ORGANIC SYNTHESIS | 2010年 / 7卷 / 05期

关键词：

Organofluorine compounds; trifluoromethyl group; bicyclic heterocycles and fused heterocycles; BIOLOGICAL EVALUATION; DERIVATIVES; DISCOVERY; POTENT; 3-(POLYFLUOROACYL)CHROMONES; CHEMISTRY; ANTITUMOR; PYRIDINES; FLUORINE; SERIES;

D O I：

10.2174/157017910792246117

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Development of efficient routes to many kinds of fluorine-containing heterocycles is an attractive area of research since these compounds are now widely recognized as important organic materials for their potential use in medicinal and agricultural scientific fields. This review survey research works on trifluoromethyl-substituted fused bicyclic heterocycles and their corresponding benzo-fused analogues over the last ten years. Different approaches for the synthesis of such systems are discussed.

引用

页码：433 / 454

页数：22

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