Partial splenectomy in children undergoing liver transplantation or venous shunt for severe hypersplenism: A case control comparative study

被引：2
作者：
Boillot, Olivier [1 ,2 ,3 ,9 ]
Chopinet, Sophie [3 ]
Gregoire, Emilie [3 ]
Milot, Laurent [4 ]
Petit, Philippe [5 ]
Rohmer, Barbara [6 ]
Roquelaure, Bertrand [7 ]
Dariel, Anne [8 ]
Panait, Nicoleta [8 ]
Hardwigsen, Jean [3 ]
Dumortier, Jerome [1 ,2 ]
机构：
[1] Hosp Civils Lyon, Edouard Herriot Hosp, Dept Digest Dis, Lyon, France
[2] Univ Claude Bernard Lyon 1, Lyon, France
[3] Aix Marseille Univ, Timone Hosp, AP HP, Dept Gen Surg & Liver Transplantat, Marseille, France
[4] Hosp Civils Lyon, Edouard Herriot Hosp, Dept Radiol, Lyon, France
[5] Timone Hosp, AP HP, Dept Pediat Radiol, Marseille, France
[6] Hosp Civils Lyon, Femme Mere Enfant Hosp, Dept Pediat, Lyon, France
[7] Timone Hosp, AP HP, Dept Pediat, Marseille, France
[8] Timone Hosp, AP HP, Dept Pediat Surg, Marseille, France
[9] Hop Edouard Herriot, Pavillon D, F-69437 Lyon 03, France
来源：
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY | 2022年 / 46卷 / 06期
关键词：
Hypersplenism; Splenomegaly; Partial splenectomy; Liver transplantation; Venous shunt; Outcome; PORTAL-HYPERTENSION; SPLENIC VEIN; THROMBOCYTOPENIA; RISK;
D O I：
10.1016/j.clinre.2022.101929
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Background and aim: Hypersplenism is a consequence of portal hypertension and splenomegaly secondary to cirrhosis or portal cavernoma in children. In order to avoid persistent hypersplenism and splenomegaly after liver transplantation (LT) or venous shunt (VS), partial splenectomy (PS) may represent a relevant therapeutic option. The aim of this retrospective study was to evaluate the results of PS performed in children presenting hypersplenism.Methods: The following end-points were evaluated: (1) reversion of hypersplenism and its dura-bility over time, (2) postoperative outcome, (3) courses of spleen size and volume and (4) com-parison to a control group in which PS was not performed.
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页数：10
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