Langerhans cell histiocytosis in the occipital condyle: a case study and a brief review of the literature

被引：0

作者：

Barbosa, Nuno Cesar ^{[1
]}

Ramos, Acacio ^{[1
,2
]}

Sagarribay, Amets ^{[3
]}

Ribeiro, Maria Jose ^{[4
]}

机构：

[1] Hosp Vila Franca Xira, Ortopedia, Vila Franca De Xira, Portugal

[2] Hosp Particular Algarve, Ortopedia, Gambelas, Portugal

[3] Hosp Dona Estefania, Neurocirurg, Lisbon, Portugal

[4] Inst Portugues Oncol Francisco Gentil, Oncol Pediat, Lisbon, Portugal

来源：

BMJ CASE REPORTS | 2020年 / 13卷 / 12期

关键词：

chemotherapy; paediatric oncology; orthopaedics; neurosurgery; EOSINOPHILIC GRANULOMA; BONE; MANAGEMENT; RECOMMENDATIONS; TORTICOLLIS; EXPERIENCE; DIAGNOSIS; CHILDREN; LESION; SKULL;

D O I：

10.1136/bcr-2020-235630

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present a case study of a 5-year-old patient, who presented with left-sided torticollis. Due to persistence of problems, a CT and an MRI were made showing a single osteolytic lesion centred on right occipital condyle. After an open biopsy, histology confirmed it to be Langerhans cell histiocytosis (LCH). Torticollis or restricted range of motion is a presenting feature in 76% of children with LCH with cervical involvement. There remains much debate on the best treatment strategy. The clinical and radiological outcomes of the case study presented on this article support the treatment of LCH with chemotherapy in cases with solitary involvement of the occipital condyle.

引用

页数：5

共 47 条

[1] Controversies and new approaches to treatment of Langerhans cell histiocytosis
Arceci, RJ
Brenner, MK
Pritchard, J
[J]. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 1998, 12 (02) : 339 - +
[2] Primary Musculoskeletal Langerhans Cell Histiocytosis in Children An Analysis for a 3-Decade Period
Arkader, Alexandre
Glotzbecker, Michael
Hosalkar, Harish S.
Dormans, John P.
[J]. JOURNAL OF PEDIATRIC ORTHOPAEDICS, 2009, 29 (02) : 201 - 207
[3] Baumgartner I, 1997, MED PEDIATR ONCOL, V28, P9, DOI 10.1002/(SICI)1096-911X(199701)28:1<9::AID-MPO3>3.0.CO
[4] 2-P
[5] Clinicopathological and Immunohistochemical Study of Head and Neck Langerhans Cell Histiocytosis from Latin America
Bedran N.R.
Carlos R.
de Andrade B.A.B.
Bueno A.P.S.
Romañach M.J.
Milito C.B.
[J]. Head and Neck Pathology, 2018, 12 (4) : 431 - 439
[6] Eosinophilic granuloma of the cervical spine
Bertram, C
Madert, A
Eggers, C
[J]. SPINE, 2002, 27 (13) : 1408 - 1413
[7] Isolated Langerhans Cell Histiocytosis Bone Lesion in Pediatric Patients: Systematic Review and Treatment Algorithm
Bezdjian, Aren
Alarfaj, Abdullah A.
Varma, Namrata
Daniel, Sam J.
[J]. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2015, 153 (05) : 751 - 757
[8] Clinicopathological pattern of cranial unifocal Langerhans cell histiocytosis: A study at medical college hospital
Bhat, Salma
Nazir, Parvez
Bashir, Humaira
Reshi, Ruby
Sheikh, Sheema
Wani, Rohi
[J]. INDIAN JOURNAL OF MEDICAL AND PAEDIATRIC ONCOLOGY, 2015, 36 (03) : 183 - 185
[9] Current therapy for Langerhans cell histiocytosis
Broadbent, V
Gadner, H
[J]. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 1998, 12 (02) : 327 - +
[10] LANGERHANS CELL HISTIOCYTOSIS IN CHILDHOOD - RESULTS FROM THE ITALIAN COOPERATIVE AIEOP-CNR-H.X 83 STUDY
CECI, A
DETERLIZZI, M
COLELLA, R
LOIACONO, G
BALDUCCI, D
SURICO, G
CASTELLO, M
TESTI, AM
DEBERNARDI, B
INDOLFI, P
MACCHIA, P
MADON, E
MANCINI, A
ROSATI, D
[J]. MEDICAL AND PEDIATRIC ONCOLOGY, 1993, 21 (04): : 259 - 264

← 1 2 3 4 5 →