Microsatellite analysis reveals high genetic diversity but low genetic structure in Ethiopian indigenous cattle populations

被引：47

作者：

Dadi, H. ^{[1
]}

Tibbo, M. ^{[2
]}

Takahashi, Y. ^{[1
]}

Nomura, K. ^{[1
]}

Hanada, H. ^{[1
]}

Amano, T. ^{[1
]}

机构：

[1] Tokyo Univ Agr, Dept Anim Sci, Lab Anim Genet & Breeding, Atsugi, Kanagawa 2430034, Japan

[2] ILRI, Addis Ababa, Ethiopia

来源：

ANIMAL GENETICS | 2008年 / 39卷 / 04期

关键词：

genetic diversity; indigenous cattle; levels of admixture; microsatellites;

D O I：

10.1111/j.1365-2052.2008.01748.x

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Ethiopian cattle are under threat from uncontrolled mating practices and are at high risk of becoming genetically homogeneous. Therefore, to evaluate genetic diversity, population structure and degree of admixture, 30 microsatellite markers were genotyped using 351 DNA samples from 10 Ethiopian cattle populations and the Holstein breed. The mean number of alleles per cattle population ranged from 6.93 +/- 2.12 in Sheko to 7.50 +/- 2.35 in Adwa. The mean observed and expected heterozygosities were 0.674 +/- 0.015 and 0.726 +/- 0.019 respectively. Ethiopian cattle populations have maintained a high level of within-population genetic differentiation (98.7%), the remainder being accounted for by differentiation among populations (1.3%). A highly significant deficiency in heterozygotes was detected within populations (F(IS) = 0.071; P < 0.001) and total inbreeding (F(IT) = 0.083; P < 0.001). The study populations were highly admixed but distinct from pure Bos taurus and Bos indicus breeds. The various levels of admixture and high genetic diversity make Ethiopian cattle populations suitable for future genetic improvement and utilization under a wide range of agro-ecologies in Ethiopia.

引用

页码：425 / 431

页数：7

共 39 条

[1] ALBERRO M, 1982, WORLD ANIM REV, P2
[2] Mitochondrial diversity and the origins of African and European cattle
Bradley, DG
MacHugh, DE
Cunningham, P
Loftus, RT
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (10) : 5131 - 5135
[3] MICROSATELLITES AND THEIR APPLICATION TO POPULATION GENETIC-STUDIES
BRUFORD, MW
WAYNE, RK
[J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 1993, 3 (06) : 939 - 943
[4] Individual-based assessment of population structure and admixture in Austrian, Croatian and German draught horses
Druml, T.
Curik, I.
Baumung, R.
Aberle, K.
Distl, O.
Soelkner, J.
[J]. HEREDITY, 2007, 98 (02) : 114 - 122
[5] Epstein H., 1984, In evolution of domesticated animals
[6] EPSTEIN H, 1971, ORIGIN DOMESTICATED
[7] Felius M., 1995, CATTLE BREEDS ENCY
[8] Goudet J., 2002, FSTAT VERSION 2 9 3
[9] Grigson C., 1991, AFR ARCHAEOL REV, V9, P119, DOI [10.1007/BF01117218, DOI 10.1007/BF01117218]
[10] Grigson C., 1989, BAR INT SERIES, P77

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