Toll Signaling in Flies and Mammals: Two Sorts of MyD88

被引:7
|
作者
Goto, Akira [1 ]
Imler, Jean-Luc [1 ,2 ]
机构
[1] CNRS, UPR9022, Inst Biol Mol & Cellulaire, F-67084 Strasbourg, France
[2] Univ Strasbourg, Fac Sci Vie, F-67083 Strasbourg, France
关键词
DROSOPHILA EMBRYO; PATHWAY;
D O I
10.1016/j.immuni.2012.04.001
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The mammalian MyD88 signaling molecule participates in Toll receptor signaling within the cytoplasm. In this issue of Immunity, Marek and Kagan (2012) report that Drosophila (d)MyD88 acts instead at the plasma membrane to sort the signaling adaptor Tube.
引用
收藏
页码:555 / 557
页数:3
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