An efficient copper-aluminum hydrotalcite catalyst for asymmetric hydrosilylation of ketones at room temperature

被引：40

作者：

Kantam, M. Lakshmi ^{[1
]}

Laha, Soumi ^{[1
]}

Yadav, Jagjit ^{[1
]}

Likhar, Pravin R. ^{[1
]}

Sreedhar, Boija ^{[1
]}

Jha, Shailendra ^{[3
]}

Bhargava, Suresh ^{[2
]}

Udayakiran, M. ^{[1
]}

Jagadeesh, B. ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

[2] RMIT Univ, Sch Appl Sci, Melbourne, Vic, Australia

[3] Jadavpur Univ, Dept Chem, Kolkata, India

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 14期

关键词：

D O I：

10.1021/ol800616p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A catalyst system consisting of a copper-aluminum hydrotalcite-chiral diphosphine ligand effects asymmetric hydrosilylation of several ketones, using polymethylhydrosiloxane (PMHS) as the stoichiometric reducing agent at room temperature, with moderate-to-excellent enantioselectivities. The catalyst is recovered by simple centrifugation, and the efficiency of the catalyst remains almost unaltered even after several cycles.

引用

页码：2979 / 2982

页数：4

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