A Comparison of Superficial and Deep Bacterial Presence in Open Fractures of the Lower Extremities

被引:6
作者
Ako-Nai, A. K. [2 ]
Ikem, I. C. [1 ]
Daniel, F. V. [2 ]
Ojo, D. O. [3 ]
Oginni, L. M.
机构
[1] Obafemi Awolowo Univ, Dept Orthopaed Surg & Traumatol, Coll Hlth Sci, Ife, Nigeria
[2] Obafemi Awolowo Univ, Fac Sci, Ife, Nigeria
[3] Obafemi Awolowo Univ Teaching, Ife, Nigeria
关键词
open fracture; wounds; bacteria flora; superficial; deep; SUSCEPTIBILITY; INFECTION;
D O I
10.1177/1534734609350549
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
This open prospective study compared the bacterial flora of superficial and deep-wound biopsies and swabs over a 2-year period in 4 different samples cultured from open fracture wounds at the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria. Samples were taken from 47 patients with factures graded according to Gustilo and Anderson's classification as grade 1 (2.1%), grade II (29.8%), grade IIIA (36.2%), and grade IIIB (31%). A total of 248 samples were cultured using standard techniques. The incidence of open fracture wounds was 78.7% in male patients and 21.3% in female patients. Tibia fractures constituted 66.1%. A total of 203 bacterial isolates were cultured from 248 samples. Gram-negative bacteria constituted 53.2% of isolates, with Escherichia coli being predominant (12.8%). Staphylococcus aureus were the predominant Gram-positive cocci (15.3%), and Staphylococcus epidermidis (13.3%) may be considered to be the major source of open fracture wound contamination. The bacterial species cultured from superficial and deep-wound swabs and biopsies were similar. Resistance to antimicrobials was high for penicillins (amoxicillin and cloxacillin), with values of 68.6% and 58.3%, respectively, for superficial bacterial species and 58.2% and 31.9%, respectively, for deep-wound biopsies.
引用
收藏
页码:197 / 202
页数:6
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