Pure red cell aplasia associated to clonal CD8+ T-cell large granular lymphocytosis:: Dependence on cyclosporin A therapy

被引：12

作者：

Coutinho, J ^{[1
]}

Lima, M ^{[1
]}

Teixeira, MD ^{[1
]}

Cabeda, JM ^{[1
]}

Leite, F ^{[1
]}

Justiça, B ^{[1
]}

机构：

[1] St Antonios Hosp, Serv Clin Haematol, P-4000 Oporto, Portugal

来源：

ACTA HAEMATOLOGICA | 1998年 / 100卷 / 04期

关键词：

CD8+ lymphocytes; cyclosporin A; large granular lymphocytes; pure red cell aplasia;

D O I：

10.1159/000040906

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This case report details a single patient with pure red cell aplasia (PRCA) associated with clonal CD3+, TCR alpha beta+, TCR-V beta 8+, CD8+, CD57+ large granular lymphocytosis whose anaemia did not respond to conventional immunosuppressive therapy but did respond to cyclosporin A (CsA). The patient has become dependent on CsA for 7 years in order to control anaemia due to associated PRCA.

引用

页码：207 / 210

页数：4

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