Prognostic impact of CSF3R mutations in favorable risk childhood acute myeloid leukemia

被引：20

作者：

Tarlock, Katherine ^{[1
,2
]}

Alonzo, Todd ^{[3
,4
]}

Wang, Yi-Cheng ^{[4
]}

Gerbing, Robert B. ^{[4
]}

Ries, Rhonda E. ^{[2
]}

Hylkema, Tiffany ^{[2
]}

Smith, Jenny L. ^{[2
]}

Maxson, Julia E. ^{[5
]}

Meshinchi, Soheil ^{[2
]}

机构：

[1] Univ Washington, Div Hematol Oncol, Seattle Childrens Hosp, Seattle, WA 98195 USA

[2] Fred Hutchinson Canc Res Ctr, Div Clin Res, 1124 Columbia St, Seattle, WA 98104 USA

[3] Univ Southern Calif, Keck Sch Med, Los Angeles, CA 90007 USA

[4] Childrens Oncol Grp, Monrovia, CA USA

[5] Oregon Hlth & Sci Univ, Knight Canc Inst, Portland, OR 97201 USA

来源：

BLOOD | 2020年 / 135卷 / 18期

基金：

美国国家卫生研究院;

关键词：

SEVERE CONGENITAL NEUTROPENIA; COLONY-STIMULATING FACTOR; CHRONIC NEUTROPHILIC LEUKEMIA; CEBPA MUTATIONS; FACTOR-RECEPTOR; GRANULOCYTE; AML; T618I; MICE;

D O I：

10.1182/blood.2019004179

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1603 / 1606

页数：4

共 25 条

[1] Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia [J].

Beekman, Renee ;

Valkhof, Marijke G. ;

Sanders, Mathijs A. ;

van Strien, Paulette M. H. ;

Haanstra, Jurgen R. ;

Broeders, Lianne ;

Geertsma-Kleinekoort, Wendy M. ;

Veerman, Anjo J. P. ;

Valk, Peter J. M. ;

Verhaak, Roel G. ;

Lowenberg, Bob ;

Touw, Ivo P. .

BLOOD, 2012, 119 (22) :5071-5077

[2] The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions (vol 24, pg 103, 2017) [J].

Bolouri, Hamid ;

Farrar, Jason E. ;

Triche, Timothy, Jr. ;

Ries, Rhonda E. ;

Lim, Emilia L. ;

Alonzo, Todd A. ;

Ma, Yussanne ;

Moore, Richard ;

Mungall, Andrew J. ;

Marra, Marco A. ;

Zhang, Jinghui ;

Ma, Xiaotu ;

Liu, Yu ;

Liu, Yanling ;

Auvil, Jaime M. Guidry ;

Davidsen, Tanja M. ;

Gesuwan, Patee ;

Hermida, Leandro C. ;

Salhia, Bodour ;

Capone, Stephen ;

Ramsingh, Giridharan ;

Zwaan, Christian Michel ;

Noort, Sanne ;

Piccolo, Stephen R. ;

Kolb, E. Anders ;

Gamis, Alan S. ;

Smith, Malcolm A. ;

Gerhard, Daniela S. ;

Meshinchi, Soheil .

NATURE MEDICINE, 2018, 24 (01) :103-+

[3] Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia [J].

Braun, Theodore P. ;

Okhovat, Mariam ;

Coblentz, Cody ;

Carratt, Sarah A. ;

Foley, Amy ;

Schonrock, Zachary ;

Smith, Brittany M. ;

Nevonen, Kimberly ;

Davis, Brett ;

Garcia, Brianna ;

LaTocha, Dorian ;

Weeder, Benjamin R. ;

Grzadkowski, Michal R. ;

Estabrook, Joey C. ;

Manning, Hannah G. ;

Watanabe-Smith, Kevin ;

Jeng, Sophia ;

Smith, Jenny L. ;

Leonti, Amanda R. ;

Ries, Rhonda E. ;

McWeeney, Shannon ;

Di Genua, Cristina ;

Drissen, Roy ;

Nerlov, Claus ;

Meshinchi, Soheil ;

Carbone, Lucia ;

Druker, Brian J. ;

Maxson, Julia E. .

NATURE COMMUNICATIONS, 2019, 10 (1)

[4] Granulocyte colony-stimulating factor receptor signaling in neutropenia, chronic neutrophilic leukemia, and related severe congenital malignancies [J].

Dwivedi, Pankaj ;

Greis, Kenneth D. .

EXPERIMENTAL HEMATOLOGY, 2017, 46 :9-20

[5] The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition [J].

Fleischman, Angela G. ;

Maxson, Julia E. ;

Luty, Samuel B. ;

Agarwal, Anupriya ;

Royer, Lacey R. ;

Abel, Melissa L. ;

MacManiman, Jason D. ;

Loriaux, Marc M. ;

Druker, Brian J. ;

Tyner, Jeffrey W. .

BLOOD, 2013, 122 (22) :3628-3631

[6] Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis:: results of a long-term survey [J].

Germeshausen, Manuela ;

Ballmaier, Matthias ;

Welte, Karl .

BLOOD, 2007, 109 (01) :93-99

[7] Expression of CEBPA is reduced in RUNX1-mutated acute myeloid leukemia [J].

Grossmann, V. ;

Bacher, U. ;

Kohlmann, A. ;

Butschalowski, K. ;

Roller, A. ;

Jeromin, S. ;

Dicker, F. ;

Kern, W. ;

Schnittger, S. ;

Haferlach, T. ;

Haferlach, C. .

BLOOD CANCER JOURNAL, 2012, 2 :e86-e86

[8] Ruxolitinib, a potent JAK1/JAK2 inhibitor, induces temporary reductions in the allelic burden of concurrent CSF3R mutations in chronic neutrophilic leukemia [J].

Gunawan, Arief S. ;

McLornan, Donal P. ;

Wilkins, Bridget ;

Waghorn, Katherine ;

Hoade, Yvette ;

Cross, Nicholas C. P. ;

Harrison, Claire N. .

HAEMATOLOGICA, 2017, 102 (06) :E238-E240

[9] Prevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group [J].

Ho, Phoenix A. ;

Alonzo, Todd A. ;

Gerbing, Robert B. ;

Pollard, Jessica ;

Stirewalt, Derek L. ;

Hurwitz, Craig ;

Heerema, Nyla A. ;

Hirsch, Betsy ;

Raimondi, Susana C. ;

Lange, Beverly ;

Franklin, Janet L. ;

Radich, Jerald P. ;

Meshinchi, Soheil .

BLOOD, 2009, 113 (26) :6558-6566

[10] NONPARAMETRIC-ESTIMATION FROM INCOMPLETE OBSERVATIONS [J].

KAPLAN, EL ;

MEIER, P .

JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 1958, 53 (282) :457-481

← 1 2 3 →