dictyBase:: a new Dictyostelium discoideum genome database

被引:67
作者
Kreppel, L
Fey, P
Gaudet, P
Just, E
Kibbe, WA
Chisholm, RL
Kimmel, AR [1 ]
机构
[1] NIDDKD, Lab CEllular & Dev Biol 50 3351, NIH, Bethesda, MD 20892 USA
[2] Northwestern Univ, Feinberg Sch Med, Ctr Med Genet, Chicago, IL 60611 USA
关键词
D O I
10.1093/nar/gkh138
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Dictyostelium discoideum is a powerful and genetically tractable model system used for the study of numerous cellular molecular mechanisms including chemotaxis, phagocytosis and signal transduction. The past 2 years have seen a significant expansion in the scope and accessibility of online resources for Dictyostelium. Recent advances have focused on the development of a new comprehensive online resource called dictyBase (http://dictybase.org). This database not only provides access to genomic data including functional annotation of genes, gene products and chromosomal mapping, but also to extensive biological information such as mutant phenotypes and corresponding reference material. In conjunction with additional sites (http://genome. imb-jena.de/dictyostelium/, http://dictyensembl. bioch.bcm.tmc.edu and http://www.sanger.ac.uk/ Projects/D-discoideum/) from the genome sequencing and assembly centers, these improvements have expanded the scope of the Dictyostelium databases making them accessible and useful to any researcher interested in comparative and functional genomics in metazoan organisms.
引用
收藏
页码:D332 / D333
页数:2
相关论文
共 9 条
[1]   BASIC LOCAL ALIGNMENT SEARCH TOOL [J].
ALTSCHUL, SF ;
GISH, W ;
MILLER, W ;
MYERS, EW ;
LIPMAN, DJ .
JOURNAL OF MOLECULAR BIOLOGY, 1990, 215 (03) :403-410
[2]   The Protein Data Bank [J].
Berman, HM ;
Westbrook, J ;
Feng, Z ;
Gilliland, G ;
Bhat, TN ;
Weissig, H ;
Shindyalov, IN ;
Bourne, PE .
NUCLEIC ACIDS RESEARCH, 2000, 28 (01) :235-242
[3]  
DEMEREC M, 1966, GENETICS, V54, P61
[4]   Saccharomyces Genome Database (SGD) provides secondary gene annotation using the Gene Ontology (GO) [J].
Dwight, SS ;
Harris, MA ;
Dolinski, K ;
Ball, CA ;
Binkley, G ;
Christie, KR ;
Fisk, DG ;
Issel-Tarver, L ;
Schroeder, M ;
Sherlock, G ;
Sethuraman, A ;
Weng, S ;
Botstein, D ;
Cherry, JM .
NUCLEIC ACIDS RESEARCH, 2002, 30 (01) :69-72
[5]   Sequence and analysis of chromosome 2 of Dictyostelium discoideum [J].
Glöckner, G ;
Eichinger, L ;
Szafranski, K ;
Pachebat, JA ;
Bankier, AT ;
Dear, PH ;
Lehmann, D ;
Baumgart, C ;
Parra, G ;
Abril, JF ;
Guigó, R ;
Kumpf, K ;
Tunggal, B ;
Cox, E ;
Quail, MA ;
Platzer, M ;
Rosenthal, A ;
Noegel, AA .
NATURE, 2002, 418 (6893) :79-85
[6]   Saccharomyces genome database [J].
Issel-Tarver, L ;
Christie, KR ;
Dolinski, K ;
Andrada, R ;
Balakrishnan, R ;
Ball, CA ;
Binkley, G ;
Dong, S ;
Dwight, SS ;
Fisk, DG ;
Harris, M ;
Schroeder, M ;
Sethuraman, A ;
Tse, K ;
Weng, S ;
Botstein, D ;
Cherry, JM .
GUIDE TO YEAST GENETICS AND MOLECULAR AND CELL BIOLOGY, PT B, 2002, 350 :329-346
[7]   Genomic database resources for Dictyostelium discoideum [J].
Kreppel, L ;
Kimmel, AR .
NUCLEIC ACIDS RESEARCH, 2002, 30 (01) :84-86
[8]  
Urushihara H, 2002, MOL CELLS, V13, P1
[9]   The Protein Data Bank and structural genomics [J].
Westbrook, J ;
Feng, ZK ;
Chen, L ;
Yang, HW ;
Berman, HM .
NUCLEIC ACIDS RESEARCH, 2003, 31 (01) :489-491