Current and Emerging Treatments of Essential Tremor

被引：33

作者：

Ondo, William George ^{[1
]}

机构：

[1] Weill Cornel, Movement Disorders Methodist Neurol Inst, Med Sch, 6560 Fannin Suite 1002, Houston, TX 77025 USA

来源：

NEUROLOGIC CLINICS | 2020年 / 38卷 / 02期

关键词：

Tremor; Essential tremor; Treatment; Botulinum toxin; Deep brain stimulation; Thalamotomy; PLACEBO-CONTROLLED TRIAL; FOCUSED ULTRASOUND THALAMOTOMY; GAMMA-KNIFE THALAMOTOMY; DOUBLE-BLIND; DOSE-ESCALATION; PILOT TRIAL; STIMULATION; LEVETIRACETAM; PROPRANOLOL; GABAPENTIN;

D O I：

10.1016/j.ncl.2020.01.002

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Established medications that improve tremor include beta-adrenergic antagonists, primidone, topiramate, and ethanol. Less consistent efficacy is reported with many other medications, usually antiepileptic drugs. A number of investigational medications, including T-type calcium channel blockers and allosteric gamma-aminobutyric acid-A modulators, are being developed for tremor. Deep brain stimulation techniques continues to be refined and focused ultrasound thalamotomy now offers an incisionless surgical option. Finally a number of peripheral electrical and mechanical devices are under development for tremor.

引用

页码：309 / +

页数：16

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