Body composition and serum prostate-specific antigen: Review and findings from Flint Men's Health Study

被引:27
作者
Beebe-Dimmer, Jennifer L.
Faerber, Gary J.
Morgenstern, Hal
Werny, David
Wojno, Kirk
Halstead-Nussloch, Bronwen
Cooney, Kathleen A.
机构
[1] Wayne State Sch Med, Karmanos Canc Inst, Detroit, MI 48201 USA
[2] Wayne State Sch Med, Dept Internal Med, Detroit, MI 48201 USA
[3] Univ Michigan, Sch Med, Dept Urol, Ann Arbor, MI USA
[4] Univ Michigan, Sch Med, Dept Internal Med, Ann Arbor, MI USA
[5] Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA
关键词
D O I
10.1016/j.urology.2007.11.049
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Recent studies have suggested that obesity is associated with lower serum prostate-specific antigen levels, perhaps influencing the recommendation for prostate biopsy and potentially explaining part of the observed poorer prognosis among obese men. African-American men have the greatest rates of prostate cancer and are more likely to die of the disease, making early detection a priority in this group. We present findings from the Flint Men's Health Study, a study of African-American men, that are consistent with Most Studies Suggesting that overweight men have prostate-specific antigen levels that are 0.15 to 0.30 n-/mL lower than those who are not overweight. We have coupled our results with a systematic review Of publications in this area.
引用
收藏
页码:554 / 560
页数:7
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