Haemolytic activity and cellular toxicity of SBA-15-type silicas: elucidating the role of the mesostructure, surface functionality and linker length

被引：22
作者：
Ferenc, Malgorzata [1 ]
Katir, Nadia [2 ]
Milowska, Katarzyna [1 ]
Bousmina, Mosto [2 ,3 ]
Majoral, Jean-Pierre [4 ]
Bryszewska, Maria [1 ,2 ]
El Kadib, Abdelkrim [2 ]
机构：
[1] Univ Lodz, Fac Biol & Environm Protect, Dept Gen Biophys, PL-90131 Lodz, Poland
[2] Euromediterranean Univ Fes UEMF, Euromed Res Inst, Div Engn, Fes Shore 30070, Fes, Morocco
[3] Hassan II Acad Sci & Technol, Rabat, Morocco
[4] CNRS, Chim Coordinat Lab, F-31077 Toulouse 4, France
来源：
JOURNAL OF MATERIALS CHEMISTRY B | 2015年 / 3卷 / 13期
关键词：
ORDERED MESOPOROUS MATERIALS; COOPERATIVE CATALYSIS; CO-CONDENSATION; POROUS SILICA; NANOPARTICLES; BIOCOMPATIBILITY; DESIGN; IMPACT; MICROSPHERES; ADSORPTION;
D O I：
10.1039/c4tb01901f
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
In this contribution, amorphous silica (a-SiO2), native SBA-15 silica as well as four functional SBA-15-type silicates modified with aminopropyl (SBA-NH2), mercaptopropyl (SBA-SH), ethylcarboxylic (SBA-COOH) and undecenoic acid (SBA-FA-COOH) were prepared by the co-condensation route under similar self-assembly and sol-gel conditions. Next, the impact of these materials on red blood cells was evaluated by studying cell haemolysis and haemoglobin adsorption. Moreover, the influence of the presence of human serum albumin (HSA) on erythrocyte haemolysis and cytotoxicity toward B14 Chinese fibroblasts were investigated. Based on these variants, the role of the mesostructure, the nature of the functional group located on the silica surface and the influence of the linker length have been elucidated.
引用
收藏
页码：2714 / 2724
页数：11
相关论文
共 75 条
[1]   Multifunctional Mesoporous Silica Nanoparticles as a Universal Platform for Drug Delivery [J].
Argyo, Christian ;
Weiss, Veronika ;
Braeuchle, Christoph ;
Bein, Thomas .
CHEMISTRY OF MATERIALS, 2014, 26 (01) :435-451
[2]   Biocompatibility of Mesoporous Silica Nanoparticles [J].
Asefa, Tewodros ;
Tao, Zhimin .
CHEMICAL RESEARCH IN TOXICOLOGY, 2012, 25 (11) :2265-2284
[3]   Single-step dispersion of functionalities on a silica surface [J].
Banet, Philippe ;
Marcotte, Nathalie ;
Lemer, Dan A. ;
Brunel, Daniel .
LANGMUIR, 2008, 24 (16) :9030-9037
[4]   A NEW FAMILY OF MESOPOROUS MOLECULAR-SIEVES PREPARED WITH LIQUID-CRYSTAL TEMPLATES [J].
BECK, JS ;
VARTULI, JC ;
ROTH, WJ ;
LEONOWICZ, ME ;
KRESGE, CT ;
SCHMITT, KD ;
CHU, CTW ;
OLSON, DH ;
SHEPPARD, EW ;
MCCULLEN, SB ;
HIGGINS, JB ;
SCHLENKER, JL .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (27) :10834-10843
[5]   A synergistic effect of albumin and fibrinogen on immunoglobulin-induced red blood cell aggregation [J].
Ben-Ami, R ;
Barshtein, G ;
Mardi, T ;
Deutch, V ;
Elkayam, O ;
Yedgar, S ;
Berliner, S .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2003, 285 (06) :H2663-H2669
[6]   Urea-containing mesoporous silica for the adsorption of Fe(III) cations [J].
Benitez, Miriam ;
Das, Debasish ;
Ferreira, Rita ;
Pischel, Uwe ;
Garcia, Hermenegildo .
CHEMISTRY OF MATERIALS, 2006, 18 (23) :5597-5603
[7]   Soft route for monodisperse gold nanoparticles confined within SH-functionalized walls of mesoporous silica [J].
Besson, Eric ;
Mehdi, Ahmad ;
Reye, Catherine ;
Corriu, Robert J. P. .
JOURNAL OF MATERIALS CHEMISTRY, 2009, 19 (27) :4746-4752
[8]   Transformable mesoporous organo-germano-silicas [J].
Brahmi, Younes ;
Katir, Nadia ;
Castel, Annie ;
El Kadib, Abdelkrim .
MICROPOROUS AND MESOPOROUS MATERIALS, 2013, 177 :75-81
[9]   Functionalized micelle-templated silicas (MTS) and their use as catalysts for fine chemicals [J].
Brunel, D .
MICROPOROUS AND MESOPOROUS MATERIALS, 1999, 27 (2-3) :329-344
[10]   Tuning Cooperativity by Controlling the Linker Length of Silica-Supported Amines in Catalysis and CO2 Capture [J].
Brunelli, Nicholas A. ;
Didas, Stephanie A. ;
Venkatasubbaiah, Krishnan ;
Jones, Christopher W. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (34) :13950-13953
12345678