Bio-engineered TiO2 nanoparticles using Ledebouria revoluta extract: Larvicidal, histopathological, antibacterial and anticancer activity

被引：82

作者：

Aswini, R. ^{[1
]}

Murugesan, S. ^{[1
]}

Kannan, Karthik ^{[2
]}

机构：

[1] Periyar Univ, Dept Bot, Salem, India

[2] Qatar Univ, Ctr Adv Mat, Doha, Qatar

来源：

INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY | 2021年 / 101卷 / 15期

关键词：

Green synthesis; XRD; HRTEM; larvicidal and cytotoxicity studies; TITANIUM-DIOXIDE NANOPARTICLES; SILVER NANOPARTICLES; GREEN SYNTHESIS; CULEX-QUINQUEFASCIATUS; ANOPHELES-STEPHENSI; AEDES-AEGYPTI; DEGRADATION; ANTIOXIDANT; TOXICITY; CARBON;

D O I：

10.1080/03067319.2020.1718668

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Titanium dioxide nanoparticles have been synthesised using bulb extract of Ledebouria revoluta. The prepared TiO2 nanoparticles were characterised by structural (XRD, FTIR), morphological (HRTEM) and optical (UV-Vis) analysis. XRD shows the bioengineered TiO2 nanoparticles exhibit an average crystalline size of 47 nm with tetragonal structure. In FTIR spectra, the peak 482 cm(-1) is indicating the presence of Ti-O stretching vibration. The morphology of bioengineered TiO2 nanoparticles shows a spherical shape. Antibacterial activity of L. revoluta bulb aqueous extract and TiO2 nanoparticles were evaluated against human pathogens. The larvicidal activity of TiO2 nanoparticles showed LC50 (18.960 mg/mL) and LC90 (77.097 mg/mL) against Aedes aegypti. Anti-lung cancer activity of TiO2 nanoparticles was examined using MTT assay and it results in IC50 value of 53.65 mu g/mL. Furthermore, bioengineered TiO2 nanoparticles will be applicable to pharmaceutical applications.

引用

页码：2926 / 2936

页数：11

共 47 条

[1] The mosquito Aedes aegypti has a large genome size and high transposable element load but contains a low proportion of transposon-specific piRNAs [J].