Measuring and Modeling Activity Coefficients in Aqueous Amino-Acid Solutions

被引：136

作者：

Held, Christoph ^{[1
]}

Cameretti, Luca F. ^{[1
]}

Sadowski, Gabriele ^{[1
]}

机构：

[1] Tech Univ Dortmund, Lab Thermodynam, Dept Biochem & Chem Engn, D-44227 Dortmund, Germany

来源：

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH | 2011年 / 50卷 / 01期

关键词：

PERTURBED-CHAIN SAFT; EQUATION-OF-STATE; PARTIAL MOLAR ENTHALPIES; FLUID THEORY EQUATION; ELECTROLYTE-SOLUTIONS; PHASE-EQUILIBRIA; WATER ACTIVITY; VAPOR-PRESSURES; GLUTAMIC-ACID; 298.15; K;

D O I：

10.1021/ie100088c

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

The perturbed-chain statistical association theory (PC-SAFT) is applied to simultaneously describe various thermodynamic properties (density, vapor-pressure depression, activity coefficient, solubility) of aqueous solutions containing an amino acid or an oligopeptide. The 28 organic compounds considered within this work are glycine, alanine, serine, proline, hydroxyproline, valine, leucine, arginine, lysine, threonine, asparagine, tyrosine, histidine, cysteine, methionine, aspartic acid, glutamic acid, alpha-ABA, alpha-isoABA, beta-ABA, gamma-ABA, alpha-AVA, gamma-AVA, diglycine, triglycine, dialanine, Gly-Ala, and Ala-Gly. If not yet available in literature, amino-acid solubility data and activity coefficients were determined experimentally. To prove the predictivity of PC-SAFT, osmotic coefficients in aqueous solutions containing two amino acids (glycine/valine and alanine/valine) were measured and predicted without applying any additional model parameters.

引用

页码：131 / 141

页数：11

共 72 条

[1] Solubilities of the common L-alpha-amino acids as a function of temperature and solution pH [J].

Amend, JP ;

Helgeson, HC .

PURE AND APPLIED CHEMISTRY, 1997, 69 (05) :935-942

[2] Solubilities of L-aspartic, DL-aspartic, DL-glutamic, p-hydroxybenzoic, o-anistic, p-anisic, and itaconic acids in water from T = 278 K to T = 345 K [J].

Apelblat, A ;

Manzurola, E .

JOURNAL OF CHEMICAL THERMODYNAMICS, 1997, 29 (12) :1527-1533

[3] VAPOR-PRESSURES OF NON-AQUEOUS ELECTROLYTE-SOLUTIONS .1. ALKALI-METAL SALTS IN METHANOL [J].

BARTHEL, J ;

NEUEDER, R ;

LAUERMANN, G .

JOURNAL OF SOLUTION CHEMISTRY, 1985, 14 (09) :621-633

[4]

BONINCONTRO A, 1978, Z NATURFORSCH A, V33, P462

[5] OSMOTIC AND ACTIVITY-COEFFICIENTS OF SOME AMINO-ACIDS AND THEIR HYDROCHLORIDE SALTS AT 298.15-K [J].

BONNER, OD .

JOURNAL OF CHEMICAL AND ENGINEERING DATA, 1982, 27 (04) :422-423

[6] Modeling of aqueous electrolyte solutions with perturbed-chain statistical associated fluid theory [J].

Cameretti, LF ;

Sadowski, G ;

Mollerup, JM .

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2005, 44 (09) :3355-3362

[7] Modeling of aqueous amino acid and polypeptide solutions with PC-SAPT [J].

Cameretti, Luca F. ;

Sadowski, Gabriele .

CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION, 2008, 47 (06) :1018-1025

[8] Solubilities of L-cystine, L-tyrosine, L-leucine, and glycine in aqueous solutions at various pHs and NaCl concentrations [J].

Carta, R ;

Tola, G .

JOURNAL OF CHEMICAL AND ENGINEERING DATA, 1996, 41 (03) :414-417

[9]

Cohn E. J., 1943, Proteins

[10] Studies in the physical chemistry of amino acids, peptides, and related substances XII Interactions between dipolar ions in aqueous solution [J].

Cohn, EJ ;

McMeekin, TL ;

Ferry, JD ;

Blanchard, MH .

JOURNAL OF PHYSICAL CHEMISTRY, 1939, 43 (01) :169-188

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