Radiation syntheses of Pectin/acrylamide (PEC/PAM) and Pectin/Diethylaminoethylmethacrylate (PEC/DEAMA) hydrogels as drug delivery systems

被引：3
作者：
Abou El Fadl, Faten I. [1 ]
Maziad, Nabila A. [1 ]
机构：
[1] Natl Ctr Radiat Res & Technol, Cairo, Egypt
来源：
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY | 2015年 / 303卷 / 01期
关键词：
Pectin; Poly acrylamide; DEAMA; Drug release; Tetracycline HCL; Hydrogel; MUCOADHESIVE POLYMERS; PECTIN; POLYSACCHARIDES; DESIGN; GEL;
D O I：
10.1007/s10967-014-3514-2
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Different pH responsive copolymer hydrogels based on pectin were prepared by the effect of radiation. The physical and chemical properties of prepared hydrogels were studied by FTIR, and TGA. Also, the prepared hydrogels were evaluated for the possible use as drug delivery system for chlortetracycline HCL as model drug. The results revealed that the swelling ratios and the release behavior of hydrogels depend mainly on the pH of the medium and the hydrogel composition.
引用
收藏
页码：623 / 630
页数：8
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