Toward High-Efficient Chiral Separation Using Hierarchically Porous HROP@Silica-Gel-Sheet Composite

被引:16
作者
Chen, Tingting [1 ,2 ]
Tan, Huiling [1 ,2 ]
Chen, Qibin [1 ,2 ]
Gu, Liangning [1 ,2 ]
Wei, Zishuai [1 ,2 ]
Liu, Honglai [1 ,2 ]
机构
[1] East China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China
[2] East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China
基金
中国国家自然科学基金;
关键词
hierarchical porosity; hyper-cross-linked polymer; composite; racemates; chiral separation; METAL-ORGANIC FRAMEWORKS; NONCOVALENT INTERACTIONS; SELECTIVE ADSORPTION; NANOPOROUS CARBONS; IBUPROFEN; ENANTIOMERS; CRYSTALLINE; RECOGNITION; MEMBRANES; MONOLITHS;
D O I
10.1021/acsami.9b17657
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Separating racemates is still a great challenge for their similarity in chemical structures and physicochemical properties. Despite exhibiting a significant potential in the adsorption separation due to their intrinsic characteristics, hierarchically porous materials utilized in enantioseparation have rarely been reported to date. Furthermore, the molding of such materials together with their hybrid organic-inorganic monoliths is generally required to meet various prerequisites in diverse large-scale industrial applications, but without sacrificing their inherently hierarchical architectures. In this work, a three-dimensional hierarchically porous organic inorganic composite was simply and feasibly prepared via integrating the micro/mesoporous hyper-cross-linked resin organic polymer (HROP) with macroporous silica gel sheet (SGS), followed by a chiral selector postmodification, named as HROP@SGS. Racemic 1-phenylethanol, ibuprofen, and naproxen could be separated only using such a piece of HROP@SGS as the filler with a solid phase extraction technique. Herein, HROP@SGS exhibited extraordinary chiral resolution performances and succeeded in achieving a complete chiral resolution. Our findings suggest that this simple strategy proposed by us, that is, combining the chiral micro/mesoporous organic materials with macroporous inorganic substrates, can be employed to prepare an unprecedented enantioseparation material, which has a promising potential in large-scale industrial applications, such as fixed-bed and membrane separation.
引用
收藏
页码:48402 / 48411
页数:10
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