Study of the mechanical property and in vitro biocompatibility of CaSiO3 ceramics

被引：160
作者：
Lin, KL [1 ]
Zhai, WY [1 ]
Ni, SY [1 ]
Chang, J [1 ]
Zeng, Y [1 ]
Qian, WJ [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Ceram, Shanghai 200050, Peoples R China
来源：
CERAMICS INTERNATIONAL | 2005年 / 31卷 / 02期
关键词：
sintering; mechanical properties; calcium silicate; ceramics; biocompatibility;
D O I：
10.1016/j.ceramint.2004.05.023
中图分类号：
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Calcium silicate (CaSiO3) ceramics were prepared by pressureless sintering. The effects of the sintering temperature and holding time on the mechanical strength, porosity and linear shrinkage of the ceramics, and the adhesion and proliferation of bone marrow mesenchymal stem cells (MMSC) were investigated. When the sintering temperature and holding time increased, the linear shrinkage of the ceramics increased and the porosity decreased. The CaSiO3 ceramics sintered at 1100 degreesC for 5 It revealed a mechanical strength of 95.03 +/- 7.11 MPa, similar to the bending strength of human cortical bone. In addition, the adhesion and proliferation of MMSC on the CaSiO3 ceramics was examined and the results showed that the ceramics supported cell adhesion and proliferation, which indicated good biocompatibility. Our results suggested that CaSiO3 ceramics might be a potential bioactive material as bone implant. (C) 2004 Elsevier Ltd and Techna Group S.r.l. All rights reserved.
引用
收藏
页码：323 / 326
页数：4
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