Unilateral Oculomotor Nerve Palsy Following Campylobacter Infection: A Mild Form of Miller Fisher Syndrome without Ataxia

被引：8
作者：
Ueno, Tatsuya [1 ]
Kon, Tomoya [1 ]
Kurihara, Ai-ichiro [2 ]
Tomiyama, Masahiko [1 ]
机构：
[1] Aomori Prefectural Cent Hosp, Dept Neurol, Aomori, Japan
[2] Aomori Rosai Hosp, Dept Neurol, Aomori, Japan
来源：
INTERNAL MEDICINE | 2017年 / 56卷 / 21期
关键词：
oculomotor nerve; oculomotor nerve palsy; ophthalmoplegia; GQ1b; anti-GQ1b antibody syndrome; campylobacter; ANTI-GQ1B IGG ANTIBODY; BRAIN-STEM ENCEPHALITIS; CLINICAL-FEATURES; OPHTHALMOPLEGIA; OPHTHALMOPARESIS; SPECTRUM;
D O I：
10.2169/internalmedicine.8824-17
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Unilateral oculomotor nerve palsy can result from various neurological disorders. We herein report the case of a 68-year-old man with complete unilateral oculomotor nerve palsy following campylobacter infection. Based on the antecedent infection and the patient's decreased tendon reflexes, incomplete Miller Fisher syndrome (MFS) without ataxia was suspected. His serum tested positive for anti-GQ1b antibodies. He recovered over a period of 87 days without immunotherapy. We conclude that incomplete MFS following campylobacter infection can cause unilateral oculomotor nerve palsy without ataxia. Mild MFS should be considered in patients presenting with unilateral isolated ophthalmoplegia and decreased tendon reflexes.
引用
收藏
页码：2929 / 2932
页数：4
相关论文
共 16 条
  • [1] SERUM ANTI-GQ(1B) IGG ANTIBODY IS ASSOCIATED WITH OPHTHALMOPLEGIA IN MILLER FISHER SYNDROME AND GUILLAIN-BARRE-SYNDROME - CLINICAL AND IMMUNOHISTOCHEMICAL STUDIES
    CHIBA, A
    KUSUNOKI, S
    OBATA, H
    MACHINAMI, R
    KANAZAWA, I
    [J]. NEUROLOGY, 1993, 43 (10) : 1911 - 1917
  • [2] Anti-GQ1b antibody syndrome: anti-ganglioside complex reactivity determines clinical spectrum
    Fukami, Y.
    Wong, A. H. Y.
    Funakoshi, K.
    Safri, A. Y.
    Shahrizaila, N.
    Yuki, N.
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2016, 23 (02) : 320 - 326
  • [3] Unilateral oculomotor nerve palsy associated with anti-GQ1b IgG antibody
    Ichikawa, H
    Kamiya, Y
    Susuki, K
    Suzuki, M
    Yuki, N
    Kawamura, M
    [J]. NEUROLOGY, 2002, 59 (06) : 957 - 958
  • [4] Bickerstaff's brainstem encephalitis and Fisher syndrome form a continuous spectrum - Clinical analysis of 581 cases
    Ito, Masafumi
    Kuwabara, Satoshi
    Odaka, Masaaki
    Misawa, Sonoko
    Koga, Michiaki
    Hirata, Koichi
    Yuki, Nobuhiro
    [J]. JOURNAL OF NEUROLOGY, 2008, 255 (05) : 674 - 682
  • [5] Unilateral Abducens Nerve Palsy as an Early Feature of Multiple Mononeuropathy Associated with Anti-GQ1b Antibody
    Kinno, Ryuta
    Ichikawa, Hiroo
    Tanigawa, Hiroto
    Itaya, Kazuhiro
    Kawamura, Mitsuru
    [J]. CASE REPORTS IN NEUROLOGY, 2011, 3 (01): : 82 - 85
  • [6] Antecedent infections in Fisher syndrome - A common pathogenesis of molecular mimicry
    Koga, M
    Gilbert, M
    Li, J
    Koike, S
    Takahashi, M
    Furukawa, K
    Hirata, K
    Yuki, N
    [J]. NEUROLOGY, 2005, 64 (09) : 1605 - 1611
  • [7] Acute ophthalmoplegia (without ataxia) associated with anti-GQ1b antibody
    Lee, S. -H.
    Lim, G. -H.
    Kim, J. S.
    Oh, S. -Y.
    Kim, J. K.
    Cha, J. -K.
    Yun, C. -H.
    Kang, J. K.
    Lee, H.
    Song, H. -K.
    Chung, K. C.
    [J]. NEUROLOGY, 2008, 71 (06) : 426 - 429
  • [8] Immunolocalization of GQ1b and Related Gangliosides in Human Extraocular Neuromuscular Junctions and Muscle Spindles
    Liu, Jing-Xia
    Willison, Hugh J.
    Pedrosa-Domellof, Fatima
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2009, 50 (07) : 3226 - 3232
  • [9] Plasmapheresis and Miller Fisher syndrome: analysis of 50 consecutive cases
    Mori, M
    Kuwabara, S
    Fukutake, T
    Hattori, T
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2002, 72 (05) : 680 - 680
  • [10] Clinical features and prognosis of Miller Fisher syndrome
    Mori, M
    Kuwabara, S
    Fukutake, T
    Yuki, N
    Hattori, T
    [J]. NEUROLOGY, 2001, 56 (08) : 1104 - 1106
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