The heterogeneity of picture-supported narratives in Alzheimer's disease

被引：39
作者：
Duong, A
Giroux, F
Tardif, A
Ska, B
机构：
[1] Inst Univ Geriatr Montreal, Ctr Rech, Montreal, PQ, Canada
[2] Univ Montreal, Ecole Orthophon & Audiol, Fac Med, Montreal, PQ, Canada
来源：
BRAIN AND LANGUAGE | 2005年 / 93卷 / 02期
关键词：
Alzheimer; aging; language; discourse; communication; cognition; heterogeneity;
D O I：
10.1016/j.bandl.2004.10.007
中图分类号：
R36 [病理学]; R76 [耳鼻咽喉科学];
学科分类号：
100104 ; 100213 ;
摘要：
This study describes discourse patterns produced by 46 Alzheimer disease (AD) patients and 53 normal elderly subjects in two picture-supported narratives. Nine measures derived from a cognitive model of discourse processing were obtained and submitted to cluster analysis. Results indicate that discourse patterns elicited from both stimuli were heterogeneous. Further, they fail to clearly differentiate between normal aging and AD in half of the AD patients. Discourse patterns are examined in light of various sources of heterogeneity including severity of cognitive impairment, subject characteristics, and task demands. The usefulness of discourse as a diagnostic and therapeutic tool is discussed. (c) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码：173 / 184
页数：12
相关论文
共 58 条
  • [1] AGNIEL A, 1993, PROTOCOLE DEVALUATIO
  • [2] Why do Alzheimer patients have difficulty with pronouns? Working memory, semantics, and reference in comprehension and production in Alzheimer's disease
    Almor, A
    Kempler, D
    MacDonald, MC
    Andersen, ES
    Tyler, LK
    [J]. BRAIN AND LANGUAGE, 1999, 67 (03) : 202 - 227
  • [3] Speech errors in Alzheimer's disease: Reevaluating morphosyntactic preservation
    Altmann, LJP
    Kempler, D
    Andersen, ES
    [J]. JOURNAL OF SPEECH LANGUAGE AND HEARING RESEARCH, 2001, 44 (05): : 1069 - 1082
  • [4] [Anonymous], DISCOURSE ANAL APPL
  • [5] [Anonymous], 2000, DSM 4 TR DIAGN STAT
  • [6] [Anonymous], 1985, CLUSTER ANAL
  • [7] A STUDY OF LANGUAGE FUNCTIONING IN ALZHEIMER PATIENTS
    APPELL, J
    KERTESZ, A
    FISMAN, M
    [J]. BRAIN AND LANGUAGE, 1982, 17 (01) : 73 - 91
  • [8] Naming ability across the adult life span
    Au, R
    Joung, P
    Nicholas, M
    Obler, LK
    Kass, R
    Albert, ML
    [J]. AGING AND COGNITION, 1995, 2 (04): : 300 - 311
  • [9] BATES E, 1999, LANG COGNITIVE PROC, V10, P487
  • [10] Bayles K. A., 1987, COMMUNICATION COGNIT
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