Nanomedicine in cancer stem cell therapy: from fringe to forefront

被引：21

作者：

Tabassum, Nazish ^{[1
]}

Verma, Vinod ^{[1
]}

Kumar, Manoj ^{[2
]}

Kumar, Ashok ^{[3
]}

Singh, Birbal ^{[4
]}

机构：

[1] Univ Allahabad, Ctr Biotechnol, Nehru Sci Complex, Allahabad 211002, Uttar Pradesh, India

[2] ICMR, NIREH, Kamla Nehru Hosp Bldg, Bhopal, India

[3] MLK Post Grad Coll, Dept Zool, Balrampur, India

[4] Indian Vet Res Inst, Reg Stn, Palampur, Himachal Prades, India

来源：

CELL AND TISSUE RESEARCH | 2018年 / 374卷 / 03期

关键词：

Nanomedicine; Nanomaterials; Nanodevice; Cancer stem cells (CSCs); Drug delivery; TARGETED THERAPY; PHASE-I/II; IN-VITRO; REXIN-G; NANOPARTICLES; DRUG; COMBINATION; DELIVERY; DOXORUBICIN; PACLITAXEL;

D O I：

10.1007/s00441-018-2928-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Nanomedicine is the spin-off of modern medicine and nanotechnology and aims to prevent and treat diseases using nanoscale materials such as biocompatible nanoparticles and nanorobots. Targeted cellular and tissue-specific clinical applications with maximal therapeutic effects and insignificant side effects could be achieved by the pursuit of nanotechnology in medicine and healthcare regimen. The majority of conventional cancer therapies eliminate the cells of the tumor but not the cancer stem cells (CSCs). Conversely, the use of nanotechnology in CSC-based therapies is an emerging field of biomedical sciences. This article summarizes the recent trends and application of nanomedicine especially in CSC therapy along with its limitations.

引用

页码：427 / 438

页数：12

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