Nanomedicine in cancer stem cell therapy: from fringe to forefront

被引：21

作者：

Tabassum, Nazish ^{[1
]}

Verma, Vinod ^{[1
]}

Kumar, Manoj ^{[2
]}

Kumar, Ashok ^{[3
]}

Singh, Birbal ^{[4
]}

机构：

[1] Univ Allahabad, Ctr Biotechnol, Nehru Sci Complex, Allahabad 211002, Uttar Pradesh, India

[2] ICMR, NIREH, Kamla Nehru Hosp Bldg, Bhopal, India

[3] MLK Post Grad Coll, Dept Zool, Balrampur, India

[4] Indian Vet Res Inst, Reg Stn, Palampur, Himachal Prades, India

来源：

CELL AND TISSUE RESEARCH | 2018年 / 374卷 / 03期

关键词：

Nanomedicine; Nanomaterials; Nanodevice; Cancer stem cells (CSCs); Drug delivery; TARGETED THERAPY; PHASE-I/II; IN-VITRO; REXIN-G; NANOPARTICLES; DRUG; COMBINATION; DELIVERY; DOXORUBICIN; PACLITAXEL;

D O I：

10.1007/s00441-018-2928-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Nanomedicine is the spin-off of modern medicine and nanotechnology and aims to prevent and treat diseases using nanoscale materials such as biocompatible nanoparticles and nanorobots. Targeted cellular and tissue-specific clinical applications with maximal therapeutic effects and insignificant side effects could be achieved by the pursuit of nanotechnology in medicine and healthcare regimen. The majority of conventional cancer therapies eliminate the cells of the tumor but not the cancer stem cells (CSCs). Conversely, the use of nanotechnology in CSC-based therapies is an emerging field of biomedical sciences. This article summarizes the recent trends and application of nanomedicine especially in CSC therapy along with its limitations.

引用

页码：427 / 438

页数：12

共 50 条

[31] Nanomedicine, an emerging therapeutic strategy for oral cancer therapy [J].

Marcazzan, Sabrina ;

Varoni, Elena Maria ;

Blanco, Elvin ;

Lodi, Giovanni ;

Ferrari, Mauro .

ORAL ONCOLOGY, 2018, 76 :1-7

[32] The potential of nanomedicine to alter cancer stem cell dynamics: the impact of extracellular vesicles [J].

Gener, Petra ;

Callejo, Patricia Gonzalez ;

Seras-Franzoso, Joaquin ;

Andrade, Fernanda ;

Rafael, Diana ;

Abasolo, Ibane ;

Schwartz, Simo, Jr. .

NANOMEDICINE, 2020, 15 (29) :2785-2800

[33] Modulating tumor hypoxia by nanomedicine for effective cancer therapy [J].

Jahanban-Esfahlan, Rana ;

de la Guardia, Miguel ;

Ahmadi, Delshad ;

Yousefi, Bahman .

JOURNAL OF CELLULAR PHYSIOLOGY, 2018, 233 (03) :2019-2031

[34] Polyoxometalates: Versatile nanomedicine candidates for precise cancer therapy [J].

Zhou, Ruyi ;

Liao, You ;

Xu, Haozhi ;

Gu, Zhanjun ;

Leng, Zhengwei .

CHEMICAL ENGINEERING JOURNAL, 2025, 512

[35] Diabetic stem cell therapy and nanomedicine: advancements in treating diabetes [J].

Khoshnevisan, Kamyar ;

Sajjadi-Jazi, Sayed Mahmoud .

JOURNAL OF DIABETES AND METABOLIC DISORDERS, 2023, 22 (02) :1805-1807

[36] Diabetic stem cell therapy and nanomedicine: advancements in treating diabetes [J].

Kamyar Khoshnevisan ;

Sayed Mahmoud Sajjadi-Jazi .

Journal of Diabetes & Metabolic Disorders, 2023, 22 :1805-1807

[37] Multimodal Nanomedicine Strategies for Targeting Cancer Cells as well as Cancer Stem Cell Signalling Mechanisms [J].

Kanwar, Jagat R. ;

Samarasinghe, Rasika M. ;

Kamalapuram, Sishir K. ;

Kanwar, Rupinder K. .

MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2017, 17 (18) :1688-1695

[38] A unique highly hydrophobic anticancer prodrug self-assembled nanomedicine for cancer therapy [J].

Ren, Guolian ;

Jiang, Mengjuan ;

Xue, Peng ;

Wang, Jing ;

Wang, Yongjun ;

Chen, Bo ;

He, Zhonggui .

Nanomedicine-Nanotechnology Biology and Medicine, 2016, 12 (08) :2273-2282

[39] Precise nanomedicine for intelligent therapy of cancer [J].

Huabing Chen ;

Zhanjun Gu ;

Hongwei An ;

Chunying Chen ;

Jie Chen ;

Ran Cui ;

Siqin Chen ;

Weihai Chen ;

Xuesi Chen ;

Xiaoyuan Chen ;

Zhuo Chen ;

Baoquan Ding ;

Qian Dong ;

Qin Fan ;

Ting Fu ;

Dayong Hou ;

Qiao Jiang ;

Hengte Ke ;

Xiqun Jiang ;

Gang Liu ;

Suping Li ;

Tianyu Li ;

Zhuang Liu ;

Guangjun Nie ;

Muhammad Ovais ;

Daiwen Pang ;

Nasha Qiu ;

Youqing Shen ;

Huayu Tian ;

Chao Wang ;

Hao Wang ;

Ziqi Wang ;

Huaping Xu ;

JiangFei Xu ;

Xiangliang Yang ;

Shuang Zhu ;

Xianchuang Zheng ;

Xianzheng Zhang ;

Yanbing Zhao ;

Weihong Tan ;

Xi Zhang ;

Yuliang Zhao .

Science China(Chemistry), 2018, 61 (12) :1503-1552

[40] Precise nanomedicine for intelligent therapy of cancer [J].