Proton-Pump Inhibitors: Do Children Break a Leg by Using Them?

被引：8

作者：

Tavares, Marta ^{[1
]}

Amil-Dias, Jorge ^{[2
]}

机构：

[1] Ctr Materno Infanil Norte, Unit Pediat Gastroenterol, Porto, Portugal

[2] Ctr Hosp Univ S Joao, Pediat Gastroenterol, Porto, Portugal

来源：

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION | 2021年 / 73卷 / 06期

关键词：

drug; eosinophilic esophagitis; fracture; gastro-esophageal reflux; proton-pump inhibitors; side-effects; stomach; BONE-MINERAL DENSITY; OMEPRAZOLE; ABSORPTION; CALCIUM; METABOLISM; FRACTURES; THERAPY; RISK;

D O I：

10.1097/MPG.0000000000003246

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The risk of bone fracture in children under proton-pump inhibitors (PPI) treatment has been the subject of recent publications and naturally raises concerns among prescribing doctors, patients and their parents. Currently, there is no consistency in those risk claims according to the available evidence and an update on it is beneficial to reduce anxiety on one hand, and prompt for well-planned studies addressing the issue on the other. Furthermore, common sense and well-founded prescriptions must be the general rule for this as for any other therapeutic drug.

引用

页码：665 / 669

页数：5

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