Hyponatraemia and congestive heart failure refractory to diuretic treatment. Utility of tolvaptan

被引：5

作者：

Pose, A. ^{[1
]}

Almenar, L. ^{[2
]}

Manzano, L. ^{[3
]}

Gavira, J. J. ^{[4
]}

Lopez Granados, A. ^{[5
]}

Delgado, J. ^{[6
]}

Aramburu, O. ^{[7
]}

Arevalo, J. C. ^{[8
]}

Mendez, M. ^{[9
]}

Comin, J. ^{[10
]}

Manito, N. ^{[11
]}

机构：

[1] Complexo Hosp Univ Santiago de Compostela, Serv Med Interna, La Coruna, Spain

[2] Hosp Univ & Politecn La Fe, Serv Cardiol, Valencia, Spain

[3] Univ Alcala de Henares, Hosp Univ Ramon y Cajal, Serv Med Interna, Madrid, Spain

[4] Clin Univ Navarra, Serv Cardiol, Pamplona, Spain

[5] Hosp Univ Reina Sofia, Serv Cardiol, Cordoba, Spain

[6] Hosp Univ 12 Octubre, Serv Cardiol, Madrid, Spain

[7] Hosp Univ Virgen de la Macarena, Serv Med Interna, Seville, Spain

[8] Hosp Comarcal Zafra, Serv Med Interna, Badajoz, Spain

[9] Hosp Univ San Carlos, Serv Med Interna, Madrid, Spain

[10] Hosp del Mar, Serv Cardiol, Barcelona, Spain

[11] Hosp Bellvitge Princeps Espanya, Serv Cardiol, Barcelona, Spain

来源：

REVISTA CLINICA ESPANOLA | 2017年 / 217卷 / 07期

关键词：

Heart failure; Congestion; Refractory; Diuretic; Tolvaptan; Recommendations; RECEPTOR ANTAGONISM; ORAL TOLVAPTAN; LOOP DIURETICS; RESISTANCE; ULTRAFILTRATION; DECONGESTION; STRATEGIES; FUROSEMIDE; MORTALITY; THIAZIDE;

D O I：

10.1016/j.rce.2017.02.013

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart failure (HF) is currently one of the most significant healthcare problems in Spain and has a continuously increasing prevalence. Advances in our understanding of the various biological responses that promote cardiac remodelling and pulmonary venous congestion constitute the basis of current treatment. This article, prepared by members of the HF groups of the Spanish Society of Cardiology and the Spanish Society of Internal Medicine, discusses the current therapeutic strategies for patients with congestion refractory to diuretic treatment. The article includes our clinical experience with the use of tolvaptan as an additional treatment for congestion associated with hyponatraemia. To this end, we propose an algorithm for the use of tolvaptan in patients with congestive HF, natraemia < 130 mEq/l and poor response to conventional diuretic treatment. (C) 2017 Elsevier Espana, S.L.U. and Sociedad Espanola de Medicina Interna (SEMI). All rights reserved.

引用

页码：398 / 404

页数：7

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