DNA-photocleaving activities of water-soluble carbohydrate-containing nonionic homooxacalix[3]arene • [60]fullerene complex

被引:21
作者
Ikeda, A
Ejima, A
Nishiguchi, K
Kikuchi, JI
Matsumoto, T
机构
[1] Nara Inst Sci & Technol, Grad Sch Mat Sci, Ikoma 6300192, Japan
[2] Kyushu Univ, Grad Sch Engn, Dept Chem & Biochem, Higashi Ku, Fukuoka 8128581, Japan
关键词
D O I
10.1246/cl.2005.308
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new water-soluble carbohydrate-containing "nonionic" homooxacalix[3]arene (2) was synthesized. 2 could solubilize [60]fullerene (C-60) into water and the resultant complex acted as an efficient DNA photocleaving reagent.
引用
收藏
页码:308 / 309
页数:2
相关论文
共 30 条
[1]   Sequence-specific modification of guanosine in DNA by a C-60-linked deoxyoligonucleotide: Evidence for a non-singlet oxygen mechanism [J].
An, YZ ;
Chen, CHB ;
Anderson, JL ;
Sigman, DS ;
Foote, CS ;
Rubin, Y .
TETRAHEDRON, 1996, 52 (14) :5179-5189
[2]   C-60 EMBEDDED IN GAMMA-CYCLODEXTRIN - A WATER-SOLUBLE FULLERENE [J].
ANDERSSON, T ;
NILSSON, K ;
SUNDAHL, M ;
WESTMAN, G ;
WENNERSTROM, O .
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1992, (08) :604-606
[3]   PHOTOPHYSICAL PROPERTIES OF C60 [J].
ARBOGAST, JW ;
DARMANYAN, AP ;
FOOTE, CS ;
RUBIN, Y ;
DIEDERICH, FN ;
ALVAREZ, MM ;
ANZ, SJ ;
WHETTEN, RL .
JOURNAL OF PHYSICAL CHEMISTRY, 1991, 95 (01) :11-12
[4]   On the mechanism of DNA cleavage by fullerenes investigated in model systems:: Electron transfer from guanosine and 8-oxo-guanosine derivatives to C60 [J].
Bernstein, R ;
Prat, F ;
Foote, CS .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (02) :464-465
[5]  
BOUTORINE AS, 1994, ANGEW CHEM INT EDIT, V33, P2462
[6]  
Da Ros T, 1999, CHEM COMMUN, P663
[7]   Optimizing the binding of fullerene inhibitors of the HIV-1 protease through predicted increases in hydrophobic desolvation [J].
Friedman, SH ;
Ganapathi, PS ;
Rubin, Y ;
Kenyon, GL .
JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (13) :2424-2429
[8]   INHIBITION OF THE HIV-1 PROTEASE BY FULLERENE DERIVATIVES - MODEL-BUILDING STUDIES AND EXPERIMENTAL-VERIFICATION [J].
FRIEDMAN, SH ;
DECAMP, DL ;
SIJBESMA, RP ;
SRDANOV, G ;
WUDL, F ;
KENYON, GL .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (15) :6506-6509
[9]   Saccharide-directed cell recognition and molecular delivery using macrocyclic saccharide clusters: Masking of hydrophobicity to enhance the saccharide specificity [J].
Fujimoto, K ;
Miyata, T ;
Aoyama, Y .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (14) :3558-3559
[10]   Singlet oxygen production from fullerene derivatives: Effect of sequential functionalization of the fullerene core [J].
Hamano, T ;
Okuda, K ;
Mashino, T ;
Hirobe, M ;
Arakane, K ;
Ryu, A ;
Mashiko, S ;
Nagano, T .
CHEMICAL COMMUNICATIONS, 1997, (01) :21-22