Fluidic photonic integrated circuit for in-line detection

被引：18

作者：

Lien, V ^{[1
]}

Zhao, K ^{[1
]}

Lo, YH ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Elect & Comp Engn, La Jolla, CA 92093 USA

来源：

APPLIED PHYSICS LETTERS | 2005年 / 87卷 / 19期

关键词：

D O I：

10.1063/1.2126141

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

We present a microfabricated fluidic photonic integrated circuit (FPIC) performing the detection function for flow cytometry. This device was entirely made of polymer using micromolding and capillary filling techniques. An array waveguide design was chosen to achieve superb sensitivity and the time-of-flight measurement for each particle flowing by. With multichannel sampling and cross-correlation analysis, the results show significant enhancement of detection sensitivity. (C) 2005 American Institute of Physics.

引用

页码：1 / 3

页数：3

共 10 条

[1] Microfluidic devices for cellomics: a review
Andersson, H
van den Berg, A
[J]. SENSORS AND ACTUATORS B-CHEMICAL, 2003, 92 (03): : 315 - 325
[2] [Anonymous], 1985, OPTICAL INTEGRATED C
[3] Chuang S. L., 2009, PHYS PHOTONIC DEVICE
[4] Fabrication of microcapillaries and waveguides for single molecule detection
Foquet, ME
Han, J
Lopez, A
Wright, W
Craighead, HG
[J]. MICRO- AND NANOFABRICATED STRUCTURES AND DEVICES FOR BIOMEDICAL ENVIRONMENTAL APPLICATIONS, 1998, 3258 : 141 - 147
[5] Micro flow cytometers with buried SU-8/SOG optical waveguides
Lee, GB
Lin, CH
Chang, GL
[J]. SENSORS AND ACTUATORS A-PHYSICAL, 2003, 103 (1-2) : 165 - 170
[6] A prealigned process of integrating optical waveguides with microfluidic devices
Lien, V
Berdichevsky, Y
Lo, YH
[J]. IEEE PHOTONICS TECHNOLOGY LETTERS, 2004, 16 (06) : 1525 - 1527
[7] LIEN V, 2003 CLEO C LAS EL O
[8] Melamed MR., 1990, FLOW CYTOMETRY SORTI
[9] PDMS-based opto-fluidic micro flow cytometer with two-color, multi-angle fluorescence detection capability using PIN photodiodes
Tung, YC
Zhang, M
Lin, CT
Kurabayashi, K
Skerlos, SJ
[J]. SENSORS AND ACTUATORS B-CHEMICAL, 2004, 98 (2-3) : 356 - 367
[10] Yariv A., 1997, Optical Electronics in Modern Communications

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