Opportunities and challenges in antiparasitic drug discovery

被引：412

作者：

Pink, R ^{[1
]}

Hudson, A ^{[1
]}

Mouriès, MA ^{[1
]}

Bendig, M ^{[1
]}

机构：

[1] UNICEF, UNDP,World Bbank, WHO, Special Programme Res & Training Trop Dis, CH-1211 Geneva, Switzerland

来源：

NATURE REVIEWS DRUG DISCOVERY | 2005年 / 4卷 / 09期

关键词：

D O I：

10.1038/nrd1824

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

New antiparasitic drugs are urgently needed to treat and control diseases such as malaria, leishmaniasis, sleeping sickness and filariasis, which affect millions of people each year. However, because the majority of those infected live in countries in which the prospects of any financial return on investment are too low to support market-driven drug discovery and development, alternative approaches are needed. In this article, challenges and opportunities for antiparasitic drug discovery are considered, highlighting some of the progress that has been made in recent years, partly through scientific advances, but also by more effective partnership between the public and private sectors.

引用

页码：727 / 740

页数：14

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