1H, 13C and 15N resonance assignments for the microtubule-binding domain of the kinetoplastid kinetochore protein KKT4 from Trypanosoma brucei

被引:3
|
作者
Ludzia, Patryk [1 ]
Akiyoshi, Bungo [1 ]
Redfield, Christina [1 ]
机构
[1] Univ Oxford, Dept Biochem, South Parks Rd, Oxford OX1 3QU, England
基金
英国惠康基金; 英国工程与自然科学研究理事会;
关键词
KKT4; Kinetoplastid; Kinetochore; Trypanosomes; NMR resonance assignments; NMR-SPECTROSCOPY; DISCOVERY;
D O I
10.1007/s12104-020-09968-1
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
KKT4 is a kinetoplastid-specific microtubule-binding kinetochore protein that lacks significant similarity to any known kinetochore or microtubule-binding proteins. Here we present the(1)H,C-13 and(15)N resonance assignments for several fragments from the microtubule-binding domain of KKT4 (KKT4(115-343)) fromTrypanosoma brucei. These assignments provide the starting point for detailed investigations of the structure, dynamics and interactions of the microtubule-binding region of KKT4.
引用
收藏
页码:309 / 315
页数:7
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