Secondary Surgery for Functional Improvement After Hand Transplantation

被引：5

作者：

Cavadas, Pedro C. ^{[1
]}

Ibanez, Javier ^{[1
]}

Thione, Alessandro ^{[1
]}

机构：

[1] Clin Cavadas, Valencia 46021, Spain

来源：

ANNALS OF PLASTIC SURGERY | 2011年 / 67卷 / 04期

关键词：

vascularized composite allotransplantation; hand transplantation; secondary surgery; acute rejection; functional result; ALLOTRANSPLANTATION; CLASSIFICATION; MANAGEMENT; INHIBITORS; AMPUTATION; SIROLIMUS;

D O I：

10.1097/SAP.0b013e31822e5c4a

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Unilateral and bilateral hand transplantations have been performed worldwide with good midterm functional results. The role of secondary surgery to improve function in the patients with hand transplant has not been uniformly agreed upon. A series of 10 secondary procedures were performed in 5 surgeries on 3 patients with bilateral upper extremity transplantation. There was 1 incidence of acute rejection after 1 procedure. The functional improvement was evaluated subjectively by the patients as substantial. Secondary procedures can upgrade function after hand transplantation and provide unique opportunities for deep-tissue biopsies. The proinflammatory stimulus of the surgery can theoretically precipitate an acute rejection. The pharmacologic interference of some immunosuppressive drugs with wound healing should also be considered.

引用

收藏

页码：421 / 422

页数：2

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