A highly selective catalytic method for the oxidative functionalization of C-H bonds

被引：971

作者：

Dick, AR ^{[1
]}

Hull, KL ^{[1
]}

Sanford, MS ^{[1
]}

机构：

[1] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 08期

关键词：

D O I：

10.1021/ja031543m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This communication describes a new and highly practical Pd(II)-catalyzed method for the regio- and chemoselective oxidative functionalization of arenes and alkanes. Carbon?hydrogen bonds of substrates that contain a variety of directing groups (e.g., pyridine, azobenzene, pyrazole, and imine derivatives) are selectively transformed into esters, ethers, and aryl-halides under mild conditions. The scope of this reaction in terms of substrate, directing group, and oxidant is described, and a preliminary catalytic cycle is proposed. Copyright © 2004 American Chemical Society.

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页码：2300 / 2301

页数：2

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