Considerations in Membrane Resealing After Preterm PROM

被引：4
作者：
Jain, Vanita Dharan [1 ]
Sciscione, Anthony [1 ]
机构：
[1] Christiana Hosp, Delaware Ctr Maternal Fetal Med, Dept Obstet & Gynecol, Div Maternal Fetal Med, Newark, DE USA
来源：
CLINICAL OBSTETRICS AND GYNECOLOGY | 2011年 / 54卷 / 02期
关键词：
PROM; membrane healing; membrane resealing; MATRIX METALLOPROTEINASES-2 AND-9; MIDTRIMESTER PREMATURE RUPTURE; ENDOGENOUS-TISSUE INHIBITORS; AMNIOTIC-FLUID VOLUME; HUMAN FETAL MEMBRANES; VITAMIN-C; POTENTIAL TREATMENT; ANTIBIOTIC-THERAPY; INFANT MORBIDITY; GELATIN SPONGE;
D O I：
10.1097/GRF.0b013e318217edaf
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Current management of preterm premature rupture of the membranes centers around the expectant management with antibiotics and steroid therapy. Membrane rupture seems to be the result of a mechanical event. Studying the physical properties of the membranes may help to gain understanding of the nature and causes of membrane rupture. This article reviews membrane mechanics, advances in membrane healing, and strategies in the prevention of membrane rupture. The physiologic mechanisms that lead to membrane rupture have not yet been fully elucidated. Models that test the biomechanics of the membranes should be used to develop strategies for repair or prevention.
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收藏
页码：351 / 357
页数：7
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