Metal-Free Intramolecular Amination: One-Pot Tandem Synthesis of 3-Substituted 4-Quinolones

被引：15
|
作者：
Liu, Qi-Lun [1 ]
Li, Qiu-Lian [1 ]
Fei, Xiang-Dong [1 ]
Zhu, Yong-Ming [1 ]
机构：
[1] Soochow Univ, Coll Pharm, Suzhou 215123, Peoples R China
来源：
ACS COMBINATORIAL SCIENCE | 2011年 / 13卷 / 01期
基金：
中国国家自然科学基金;
关键词：
quinolones; metal-free; one-pot; intramolecular amination; CROSS-COUPLING REACTIONS; DERIVATIVES; CYCLIZATION; INHIBITORS; QUINOLONE; CATALYST;
D O I：
10.1021/co1000103
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
3-Substituted 4-quinolones were synthesized using a one-pot metal-free strategy in moderate to quantitative yields. Carried out in dimethylsulfoxide (DMSO) via a sequential addition of materials, the methodology is tolerant of a wide range of functional groups and applicable to library synthesis.
引用
收藏
页码：19 / 23
页数：5
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