Refeeding encephalopathy in a patient with severe hypophosphataemia and hyperammonaemia

被引:11
作者
Becker, S. [1 ]
Dam, G. [1 ]
Hvas, C. L. [1 ]
机构
[1] Aarhus Univ Hosp, Dept Gastroenterol & Hepatol, DK-8000 Aarhus C, Denmark
关键词
D O I
10.1038/ejcn.2014.244
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The refeeding syndrome is a potentially fatal condition that affects multiple organ systems. It is the consequence of fluid and electrolyte shifts that may occur in a malnourished patient following the introduction of nutrition therapy. The most prominent characteristic is hypophosphataemia. Although hyperammonaemia is usually seen in decompensated liver cirrhosis or acute liver failure, it may occur in other settings. We report a clinical case of prolonged and severe encephalopathy accompanied by hypophosphataemia and hyperammonaemia in a 59-year-old woman with no preexisting liver disease, urea cycle defects or portosystemic shunting. We suggest that these biochemical abnormalities were caused by uncontrolled refeeding and that the clinical picture was consistent with refeeding encephalopathy.
引用
收藏
页码:279 / 281
页数:3
相关论文
共 10 条
  • [1] Amer Assoc Study Liver Dis, 2014, J HEPATOL, V61, P642, DOI 10.1016/j.jhep.2014.05.042
  • [2] Hypophosphatemic encephalopathy in a CAPD patient
    Ardalan, Mohammad R.
    Pourafkari, Leili
    Tubbs, R. Shane
    Shoja, Mohammadall M.
    [J]. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2008, 335 (06) : 492 - 494
  • [3] CONTROL OF UREA SYNTHESIS AND AMMONIA UTILIZATION IN PROTEIN-DEPRIVATION AND REFEEDING
    FELIPO, V
    MINANA, MD
    GRISOLIA, S
    [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1991, 285 (02) : 351 - 356
  • [4] HYPERAMMONEMIC ENCEPHALOPATHY DUE TO ESSENTIAL AMINO-ACID HYPERALIMENTATION
    GRAZER, RE
    SUTTON, JM
    FRIEDSTROM, S
    MCBARRON, FD
    [J]. ARCHIVES OF INTERNAL MEDICINE, 1984, 144 (11) : 2278 - 2279
  • [5] Clinical and biochemical aspects of primary and secondary hyperammonemic disorders
    Haeberle, Johannes
    [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2013, 536 (02) : 101 - 108
  • [6] Centropontine Myelinolysis Related to Refeeding Syndrome in an Adolescent Suffering from Anorexia Nervosa
    Leroy, Sandrine
    Gout, Ariel
    Husson, Beatrice
    de Tournemire, Renault
    Tardieu, Marc
    [J]. NEUROPEDIATRICS, 2012, 43 (03) : 152 - 154
  • [7] Hyperammonemic encephalopathy caused by carnitine deficiency
    Limketkai, Berkeley N.
    Zucker, Stephen D.
    [J]. JOURNAL OF GENERAL INTERNAL MEDICINE, 2008, 23 (02) : 210 - 213
  • [8] A possible hypophosphatemia-induced life-threatening encephalopathy in diabetic ketoacidosis:: A case report
    Megarbane, Bruno
    Guerrier, Gilles
    Blancher, Anne
    Meas, Taly
    Guillausseau, Pierre-Jean
    Baud, Frederic J.
    [J]. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2007, 333 (06) : 384 - 386
  • [9] HYPERAMMONEMIA IN MARASMIC CHILDREN
    MORSY, MR
    MADINA, H
    SHARAF, SA
    SOLIMAN, AT
    ELZALABANY, MM
    RAMADAN, MAF
    [J]. JOURNAL OF TROPICAL PEDIATRICS, 1994, 40 (02) : 97 - 99
  • [10] Refeeding syndrome: a clinical review
    Ormerod, Clare
    Farrer, Kirstine
    Harper, Lindsay
    Lal, Simon
    [J]. BRITISH JOURNAL OF HOSPITAL MEDICINE, 2010, 71 (12) : 686 - 690